The origin of prokaryotic C2H2 zinc finger regulators

Naima Bouhouche, Michael Syvanen, Clarence I. Kado

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


C2H2 zinc finger bearing proteins are a large superfamily of nucleic acid binding proteins, which constitute a major subset of eukaryotic transcription factors. Although originally thought to occur only in eukaryotes, a novel C2H2 zinc finger transcription factor, Ros, which regulates both prokaryotic and eukaryotic promoters has been found in bacteria. Phylogenically, Ros is distantly related to eukaryotic zinc finger regulators.

Original languageEnglish (US)
Pages (from-to)77-81
Number of pages5
JournalTrends in Microbiology
Issue number2
StatePublished - Feb 1 2000

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology


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