The organisation of the multigene family which encodes the major cell surface protein, pMGA, of Mycoplasma gallisepticum

P. F. Markham, M. D. Glew, Jane E Sykes, T. R. Bowden, T. D. Pollocks, G. F. Browning, K. G. Whithear, I. D. Walker

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

The genome of the avian pathogen Mycoplasma gallisepticum contains a number of related genes for putative adhesion molecules (pMGA). Cloning and sequence analysis of several pMGA genes suggested that all of them might be transcriptionally and translationally functional. Analysis of the gene sequence encoding the sole pMGA variant expressed in vitro in the S6 strain (pMGA1.1) revealed no unambiguous feature that could account for its unique expression. It is estimated that the pMGA gene family may contain up to 50 members, and its possible role is discussed herein.

Original languageEnglish (US)
Pages (from-to)347-352
Number of pages6
JournalFEBS Letters
Volume352
Issue number3
DOIs
StatePublished - Oct 3 1994
Externally publishedYes

Keywords

  • Adhesin
  • Gene expression
  • Mycoplasma
  • Promoter
  • Sequence variability

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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