The Non-Human Primate Model for Early Human Development

Stuart A Meyers, Renee Riejo-Pera

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Non-human primates (NHPs) have been shown to be highly relevant models for studies of human infectious disease and fundamental pathophysiology. NHPs have also been used to address issues related to women's health, assisted reproduction, fetal well-being, and miscarriage, and have been shown to be highly relevant models for studies on assisted reproduction, gamete biology, endocrine control of gamete production, and behavior. This chapter outlines the importance of NHP models for development of understanding of human development and infertility. We discuss the advantages of the models for applications that include assisted reproductive technology (ART), as well as for studies into early embryo development. We compare developmental landmarks of timing of embryo cleavage and cytokinesis in primates and discuss some research applications for understanding these processes.

Original languageEnglish (US)
Title of host publicationProgress in Human Reproduction: Updates and New Horizons
PublisherWiley Blackwell
Pages339-353
Number of pages15
ISBN (Electronic)9781118849613
ISBN (Print)9781118849583
DOIs
StatePublished - Jan 3 2017

Keywords

  • ART
  • Embryo development
  • Non-human primates
  • Non-invasive embryo imaging
  • Post-fertilization events

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Meyers, S. A., & Riejo-Pera, R. (2017). The Non-Human Primate Model for Early Human Development. In Progress in Human Reproduction: Updates and New Horizons (pp. 339-353). Wiley Blackwell. https://doi.org/10.1002/9781118849613.ch9