Abstract
Non-human primates (NHPs) have been shown to be highly relevant models for studies of human infectious disease and fundamental pathophysiology. NHPs have also been used to address issues related to women's health, assisted reproduction, fetal well-being, and miscarriage, and have been shown to be highly relevant models for studies on assisted reproduction, gamete biology, endocrine control of gamete production, and behavior. This chapter outlines the importance of NHP models for development of understanding of human development and infertility. We discuss the advantages of the models for applications that include assisted reproductive technology (ART), as well as for studies into early embryo development. We compare developmental landmarks of timing of embryo cleavage and cytokinesis in primates and discuss some research applications for understanding these processes.
| Original language | English (US) |
|---|---|
| Title of host publication | Progress in Human Reproduction: Updates and New Horizons |
| Publisher | Wiley Blackwell |
| Pages | 339-353 |
| Number of pages | 15 |
| ISBN (Electronic) | 9781118849613 |
| ISBN (Print) | 9781118849583 |
| DOIs | |
| State | Published - Jan 3 2017 |
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Keywords
- ART
- Embryo development
- Non-human primates
- Non-invasive embryo imaging
- Post-fertilization events
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
The Non-Human Primate Model for Early Human Development. / Meyers, Stuart A; Riejo-Pera, Renee.
Progress in Human Reproduction: Updates and New Horizons. Wiley Blackwell, 2017. p. 339-353.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - The Non-Human Primate Model for Early Human Development
AU - Meyers, Stuart A
AU - Riejo-Pera, Renee
PY - 2017/1/3
Y1 - 2017/1/3
N2 - Non-human primates (NHPs) have been shown to be highly relevant models for studies of human infectious disease and fundamental pathophysiology. NHPs have also been used to address issues related to women's health, assisted reproduction, fetal well-being, and miscarriage, and have been shown to be highly relevant models for studies on assisted reproduction, gamete biology, endocrine control of gamete production, and behavior. This chapter outlines the importance of NHP models for development of understanding of human development and infertility. We discuss the advantages of the models for applications that include assisted reproductive technology (ART), as well as for studies into early embryo development. We compare developmental landmarks of timing of embryo cleavage and cytokinesis in primates and discuss some research applications for understanding these processes.
AB - Non-human primates (NHPs) have been shown to be highly relevant models for studies of human infectious disease and fundamental pathophysiology. NHPs have also been used to address issues related to women's health, assisted reproduction, fetal well-being, and miscarriage, and have been shown to be highly relevant models for studies on assisted reproduction, gamete biology, endocrine control of gamete production, and behavior. This chapter outlines the importance of NHP models for development of understanding of human development and infertility. We discuss the advantages of the models for applications that include assisted reproductive technology (ART), as well as for studies into early embryo development. We compare developmental landmarks of timing of embryo cleavage and cytokinesis in primates and discuss some research applications for understanding these processes.
KW - ART
KW - Embryo development
KW - Non-human primates
KW - Non-invasive embryo imaging
KW - Post-fertilization events
UR - http://www.scopus.com/inward/record.url?scp=85017460712&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017460712&partnerID=8YFLogxK
U2 - 10.1002/9781118849613.ch9
DO - 10.1002/9781118849613.ch9
M3 - Chapter
AN - SCOPUS:85017460712
SN - 9781118849583
SP - 339
EP - 353
BT - Progress in Human Reproduction: Updates and New Horizons
PB - Wiley Blackwell
ER -