The neural bases of amusement and sadness

A comparison of block contrast and subject-specific emotion intensity regression approaches

Philip R Goldin, Cendri A C Hutcherson, Kevin N. Ochsner, Gary H. Glover, John D E Gabrieli, James J. Gross

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

Neuroimaging studies have made substantial progress in elucidating the neural bases of emotion. However, few studies to date have directly addressed the subject-specific, time-varying nature of emotional responding. In the present study, we employed functional magnetic resonance imaging to examine the neural bases of two common emotions-amusement and sadness-using both (a) a stimulus-based block contrast approach and (b) a subject-specific regression analysis using continuous ratings of emotional intensity. Thirteen women viewed a set of nine 2-min amusing, sad, or neutral film clips two times. During the first viewing, participants watched the film stimuli. During the second viewing, they made continuous ratings of the intensity of their own amusement and sadness during the first film viewing. For sad films, both block contrast and subject-specific regression approaches resulted in activations in medial prefrontal cortex, inferior frontal gyrus, superior temporal gyrus, precuneus, lingual gyrus, amygdala, and thalamus. For amusing films, the subject-specific regression analysis demonstrated significant activations not detected by the block contrast in medial, inferior frontal gyrus, dorsolateral prefrontal cortex, posterior cingulate, temporal lobes, hippocampus, thalamus, and caudate. These results suggest a relationship between emotion-specific temporal dynamics and the sensitivity of different data analytic methods for identifying emotion-related neural responses. These findings shed light on the neural bases of amusement and sadness, and highlight the value of using emotional film stimuli and subject-specific continuous emotion ratings to characterize the dynamic, time-varying components of emotional responses.

Original languageEnglish (US)
Pages (from-to)26-36
Number of pages11
JournalNeuroImage
Volume27
Issue number1
DOIs
StatePublished - Aug 1 2005
Externally publishedYes

Fingerprint

Prefrontal Cortex
Emotions
Motion Pictures
Temporal Lobe
Thalamus
Regression Analysis
Occipital Lobe
Parietal Lobe
Gyrus Cinguli
Amygdala
Surgical Instruments
Neuroimaging
Hippocampus
Magnetic Resonance Imaging

Keywords

  • Amusement
  • Emotion
  • Neural bases
  • Sadness

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

The neural bases of amusement and sadness : A comparison of block contrast and subject-specific emotion intensity regression approaches. / Goldin, Philip R; Hutcherson, Cendri A C; Ochsner, Kevin N.; Glover, Gary H.; Gabrieli, John D E; Gross, James J.

In: NeuroImage, Vol. 27, No. 1, 01.08.2005, p. 26-36.

Research output: Contribution to journalArticle

Goldin, Philip R ; Hutcherson, Cendri A C ; Ochsner, Kevin N. ; Glover, Gary H. ; Gabrieli, John D E ; Gross, James J. / The neural bases of amusement and sadness : A comparison of block contrast and subject-specific emotion intensity regression approaches. In: NeuroImage. 2005 ; Vol. 27, No. 1. pp. 26-36.
@article{5e105130fcbb4695914feaf9726513fd,
title = "The neural bases of amusement and sadness: A comparison of block contrast and subject-specific emotion intensity regression approaches",
abstract = "Neuroimaging studies have made substantial progress in elucidating the neural bases of emotion. However, few studies to date have directly addressed the subject-specific, time-varying nature of emotional responding. In the present study, we employed functional magnetic resonance imaging to examine the neural bases of two common emotions-amusement and sadness-using both (a) a stimulus-based block contrast approach and (b) a subject-specific regression analysis using continuous ratings of emotional intensity. Thirteen women viewed a set of nine 2-min amusing, sad, or neutral film clips two times. During the first viewing, participants watched the film stimuli. During the second viewing, they made continuous ratings of the intensity of their own amusement and sadness during the first film viewing. For sad films, both block contrast and subject-specific regression approaches resulted in activations in medial prefrontal cortex, inferior frontal gyrus, superior temporal gyrus, precuneus, lingual gyrus, amygdala, and thalamus. For amusing films, the subject-specific regression analysis demonstrated significant activations not detected by the block contrast in medial, inferior frontal gyrus, dorsolateral prefrontal cortex, posterior cingulate, temporal lobes, hippocampus, thalamus, and caudate. These results suggest a relationship between emotion-specific temporal dynamics and the sensitivity of different data analytic methods for identifying emotion-related neural responses. These findings shed light on the neural bases of amusement and sadness, and highlight the value of using emotional film stimuli and subject-specific continuous emotion ratings to characterize the dynamic, time-varying components of emotional responses.",
keywords = "Amusement, Emotion, Neural bases, Sadness",
author = "Goldin, {Philip R} and Hutcherson, {Cendri A C} and Ochsner, {Kevin N.} and Glover, {Gary H.} and Gabrieli, {John D E} and Gross, {James J.}",
year = "2005",
month = "8",
day = "1",
doi = "10.1016/j.neuroimage.2005.03.018",
language = "English (US)",
volume = "27",
pages = "26--36",
journal = "NeuroImage",
issn = "1053-8119",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - The neural bases of amusement and sadness

T2 - A comparison of block contrast and subject-specific emotion intensity regression approaches

AU - Goldin, Philip R

AU - Hutcherson, Cendri A C

AU - Ochsner, Kevin N.

AU - Glover, Gary H.

AU - Gabrieli, John D E

AU - Gross, James J.

PY - 2005/8/1

Y1 - 2005/8/1

N2 - Neuroimaging studies have made substantial progress in elucidating the neural bases of emotion. However, few studies to date have directly addressed the subject-specific, time-varying nature of emotional responding. In the present study, we employed functional magnetic resonance imaging to examine the neural bases of two common emotions-amusement and sadness-using both (a) a stimulus-based block contrast approach and (b) a subject-specific regression analysis using continuous ratings of emotional intensity. Thirteen women viewed a set of nine 2-min amusing, sad, or neutral film clips two times. During the first viewing, participants watched the film stimuli. During the second viewing, they made continuous ratings of the intensity of their own amusement and sadness during the first film viewing. For sad films, both block contrast and subject-specific regression approaches resulted in activations in medial prefrontal cortex, inferior frontal gyrus, superior temporal gyrus, precuneus, lingual gyrus, amygdala, and thalamus. For amusing films, the subject-specific regression analysis demonstrated significant activations not detected by the block contrast in medial, inferior frontal gyrus, dorsolateral prefrontal cortex, posterior cingulate, temporal lobes, hippocampus, thalamus, and caudate. These results suggest a relationship between emotion-specific temporal dynamics and the sensitivity of different data analytic methods for identifying emotion-related neural responses. These findings shed light on the neural bases of amusement and sadness, and highlight the value of using emotional film stimuli and subject-specific continuous emotion ratings to characterize the dynamic, time-varying components of emotional responses.

AB - Neuroimaging studies have made substantial progress in elucidating the neural bases of emotion. However, few studies to date have directly addressed the subject-specific, time-varying nature of emotional responding. In the present study, we employed functional magnetic resonance imaging to examine the neural bases of two common emotions-amusement and sadness-using both (a) a stimulus-based block contrast approach and (b) a subject-specific regression analysis using continuous ratings of emotional intensity. Thirteen women viewed a set of nine 2-min amusing, sad, or neutral film clips two times. During the first viewing, participants watched the film stimuli. During the second viewing, they made continuous ratings of the intensity of their own amusement and sadness during the first film viewing. For sad films, both block contrast and subject-specific regression approaches resulted in activations in medial prefrontal cortex, inferior frontal gyrus, superior temporal gyrus, precuneus, lingual gyrus, amygdala, and thalamus. For amusing films, the subject-specific regression analysis demonstrated significant activations not detected by the block contrast in medial, inferior frontal gyrus, dorsolateral prefrontal cortex, posterior cingulate, temporal lobes, hippocampus, thalamus, and caudate. These results suggest a relationship between emotion-specific temporal dynamics and the sensitivity of different data analytic methods for identifying emotion-related neural responses. These findings shed light on the neural bases of amusement and sadness, and highlight the value of using emotional film stimuli and subject-specific continuous emotion ratings to characterize the dynamic, time-varying components of emotional responses.

KW - Amusement

KW - Emotion

KW - Neural bases

KW - Sadness

UR - http://www.scopus.com/inward/record.url?scp=22044442846&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=22044442846&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2005.03.018

DO - 10.1016/j.neuroimage.2005.03.018

M3 - Article

VL - 27

SP - 26

EP - 36

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

IS - 1

ER -