The nervous heart

Crystal M Ripplinger, Sami F. Noujaim, Dominik Linz

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Many cardiac electrophysiological abnormalities are accompanied by autonomic nervous system dysfunction. Here, we review mechanisms by which the cardiac nervous system controls normal and abnormal excitability and may contribute to atrial and ventricular tachyarrhythmias. Moreover, we explore the potential antiarrhythmic and/or arrhythmogenic effects of modulating the autonomic nervous system by several strategies, including ganglionated plexi ablation, vagal and spinal cord stimulations, and renal sympathetic denervation as therapies for atrial and ventricular arrhythmias.

Original languageEnglish (US)
Pages (from-to)199-209
Number of pages11
JournalProgress in Biophysics and Molecular Biology
Volume120
Issue number1-3
DOIs
StatePublished - Jan 1 2016

Fingerprint

Autonomic Nervous System
Spinal Cord Stimulation
Sympathectomy
Tachycardia
Nervous System
Cardiac Arrhythmias
Kidney
Therapeutics

Keywords

  • Atrial fibrillation
  • Autonomic control
  • Cardiac nerves
  • Ventricular tachycardia/fibrillation

ASJC Scopus subject areas

  • Molecular Biology
  • Biophysics

Cite this

The nervous heart. / Ripplinger, Crystal M; Noujaim, Sami F.; Linz, Dominik.

In: Progress in Biophysics and Molecular Biology, Vol. 120, No. 1-3, 01.01.2016, p. 199-209.

Research output: Contribution to journalArticle

Ripplinger, Crystal M ; Noujaim, Sami F. ; Linz, Dominik. / The nervous heart. In: Progress in Biophysics and Molecular Biology. 2016 ; Vol. 120, No. 1-3. pp. 199-209.
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