Abstract
Many cardiac electrophysiological abnormalities are accompanied by autonomic nervous system dysfunction. Here, we review mechanisms by which the cardiac nervous system controls normal and abnormal excitability and may contribute to atrial and ventricular tachyarrhythmias. Moreover, we explore the potential antiarrhythmic and/or arrhythmogenic effects of modulating the autonomic nervous system by several strategies, including ganglionated plexi ablation, vagal and spinal cord stimulations, and renal sympathetic denervation as therapies for atrial and ventricular arrhythmias.
Original language | English (US) |
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Pages (from-to) | 199-209 |
Number of pages | 11 |
Journal | Progress in Biophysics and Molecular Biology |
Volume | 120 |
Issue number | 1-3 |
DOIs | |
State | Published - Jan 1 2016 |
Keywords
- Atrial fibrillation
- Autonomic control
- Cardiac nerves
- Ventricular tachycardia/fibrillation
ASJC Scopus subject areas
- Molecular Biology
- Biophysics