Abstract
This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 20-26 |
| Number of pages | 7 |
| Journal | Biochimica et Biophysica Acta - Molecular Cell Research |
| Volume | 1793 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2009 |
Keywords
- Dynamin
- Membrane dynamic
- Mitochondrial fusion
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology
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Cite this
Hoppins, S., & Nunnari, J. (2009). The molecular mechanism of mitochondrial fusion. Biochimica et Biophysica Acta - Molecular Cell Research, 1793(1), 20-26. https://doi.org/10.1016/j.bbamcr.2008.07.005