The molecular mechanism of mitochondrial fusion

Suzanne Hoppins; Jodi Nunnari

doi:10.1016/j.bbamcr.2008.07.005

The molecular mechanism of mitochondrial fusion

Suzanne Hoppins, Jodi Nunnari

Molecular and Cellular Biology

Research output: Contribution to journal › Article

99 Scopus citations

Abstract

This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion.

Original language	English (US)
Pages (from-to)	20-26
Number of pages	7
Journal	Biochimica et Biophysica Acta - Molecular Cell Research
Volume	1793
Issue number	1
DOIs	https://doi.org/10.1016/j.bbamcr.2008.07.005
State	Published - Jan 2009

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Keywords

Dynamin
Membrane dynamic
Mitochondrial fusion

ASJC Scopus subject areas

Cell Biology
Molecular Biology

Cite this

Hoppins, S., & Nunnari, J. (2009). The molecular mechanism of mitochondrial fusion. Biochimica et Biophysica Acta - Molecular Cell Research, 1793(1), 20-26. https://doi.org/10.1016/j.bbamcr.2008.07.005

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Access to Document

10.1016/j.bbamcr.2008.07.005