The molecular mechanism of mitochondrial fusion

Suzanne Hoppins, Jodi Nunnari

Research output: Contribution to journalArticle

103 Scopus citations

Abstract

This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion.

Original languageEnglish (US)
Pages (from-to)20-26
Number of pages7
JournalBiochimica et Biophysica Acta - Molecular Cell Research
Volume1793
Issue number1
DOIs
StatePublished - Jan 2009

Keywords

  • Dynamin
  • Membrane dynamic
  • Mitochondrial fusion

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

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