The metastasis associated protein S100A4: Role in tumour progression and metastasis

D. M. Helfman, Edward Kim, E. Lukanidin, M. Grigorian

Research output: Contribution to journalArticle

180 Scopus citations

Abstract

The metastasis associated protein S100A4 is a small calcium binding protein that is associated with metastatic tumors and appears to be a molecular marker for clinical prognosis. Below we discuss its biochemical properties and possible cellular functions in metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation.

Original languageEnglish (US)
Pages (from-to)1955-1958
Number of pages4
JournalBritish Journal of Cancer
Volume92
Issue number11
DOIs
StatePublished - Jun 6 2005
Externally publishedYes

Keywords

  • Angiogenesis
  • Apoptosis
  • Breast cancer
  • Invasion
  • Motility
  • Prognosis

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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