The metastasis associated protein S100A4: Role in tumour progression and metastasis

D. M. Helfman, Edward Kim, E. Lukanidin, M. Grigorian

Research output: Contribution to journalArticle

177 Citations (Scopus)

Abstract

The metastasis associated protein S100A4 is a small calcium binding protein that is associated with metastatic tumors and appears to be a molecular marker for clinical prognosis. Below we discuss its biochemical properties and possible cellular functions in metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation.

Original languageEnglish (US)
Pages (from-to)1955-1958
Number of pages4
JournalBritish Journal of Cancer
Volume92
Issue number11
DOIs
StatePublished - Jun 6 2005
Externally publishedYes

Fingerprint

Neoplasm Metastasis
Calcium-Binding Proteins
Cell Movement
Neoplasms
Biomarkers
Apoptosis
S100 Calcium-Binding Protein A4

Keywords

  • Angiogenesis
  • Apoptosis
  • Breast cancer
  • Invasion
  • Motility
  • Prognosis

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

The metastasis associated protein S100A4 : Role in tumour progression and metastasis. / Helfman, D. M.; Kim, Edward; Lukanidin, E.; Grigorian, M.

In: British Journal of Cancer, Vol. 92, No. 11, 06.06.2005, p. 1955-1958.

Research output: Contribution to journalArticle

Helfman, D. M. ; Kim, Edward ; Lukanidin, E. ; Grigorian, M. / The metastasis associated protein S100A4 : Role in tumour progression and metastasis. In: British Journal of Cancer. 2005 ; Vol. 92, No. 11. pp. 1955-1958.
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