The major sigma factor (RpoD) from Helicobacter pylori and other gram- negative bacteria shows an enhanced rate of divergence

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Abstract

Sequence analysis of the Helicobacter pylori major sigma factor (RpoD) shows that it is highly divergent, which may be related to the marked diversity of the H. pylori chromosome. Furthermore, the rate of divergence of RpoD among other gram-negative bacteria is much greater than that among gram- positive bacteria. This suggests that RpoD from gram-negative bacteria is functionally less constrained than that from gram-positive bacteria.

Original languageEnglish (US)
Pages (from-to)6196-6200
Number of pages5
JournalJournal of Bacteriology
Volume179
Issue number19
StatePublished - 1997

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

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