The longevity of immunoglobulin preservation in canine skin utilizing Michel's fixative

Peter J. Ihrke, Anthony A. Stannard, Alex Ardans, Sharon G. Yaskulski

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Skin biopsy specimens from 7 dogs with immune-mediated skin diseases diagnosed by routine histology and 5 dogs with other skin diseases were placed in Michel's transport medium for 4 to 9 years. Direct immunofluorescence yielded positive results in tissue samples from 3 dogs with pemphigus foliaceus and 2 dogs with discoid lupus erythematosus. Direct immunofluorescence was not seen in tissue samples from 1 dog with pemphigus foliaceus and 5 dogs with non immune-mediated skin diseases. Direct immunofluorescence was seen in skin biopsy specimens maintained in Michel's medium for 4 to 8 years.

Original languageEnglish (US)
Pages (from-to)161-170
Number of pages10
JournalVeterinary Immunology and Immunopathology
Volume9
Issue number2
DOIs
StatePublished - Jan 1 1985
Externally publishedYes

Fingerprint

Fixatives
skin (animal)
immunoglobulins
Canidae
Immunoglobulins
Dogs
Direct Fluorescent Antibody Technique
Skin
dogs
skin diseases
pemphigus (skin disease)
Skin Diseases
fluorescent antibody technique
Pemphigus
biopsy
Discoid Lupus Erythematosus
Biopsy
lupus erythematosus
histology
Histology

ASJC Scopus subject areas

  • Immunology
  • veterinary(all)

Cite this

The longevity of immunoglobulin preservation in canine skin utilizing Michel's fixative. / Ihrke, Peter J.; Stannard, Anthony A.; Ardans, Alex; Yaskulski, Sharon G.

In: Veterinary Immunology and Immunopathology, Vol. 9, No. 2, 01.01.1985, p. 161-170.

Research output: Contribution to journalArticle

Ihrke, Peter J. ; Stannard, Anthony A. ; Ardans, Alex ; Yaskulski, Sharon G. / The longevity of immunoglobulin preservation in canine skin utilizing Michel's fixative. In: Veterinary Immunology and Immunopathology. 1985 ; Vol. 9, No. 2. pp. 161-170.
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