TY - JOUR
T1 - The longevity of immunoglobulin preservation in canine skin utilizing Michel's fixative
AU - Ihrke, Peter J.
AU - Stannard, Anthony A.
AU - Ardans, Alex
AU - Yaskulski, Sharon G.
PY - 1985/1/1
Y1 - 1985/1/1
N2 - Skin biopsy specimens from 7 dogs with immune-mediated skin diseases diagnosed by routine histology and 5 dogs with other skin diseases were placed in Michel's transport medium for 4 to 9 years. Direct immunofluorescence yielded positive results in tissue samples from 3 dogs with pemphigus foliaceus and 2 dogs with discoid lupus erythematosus. Direct immunofluorescence was not seen in tissue samples from 1 dog with pemphigus foliaceus and 5 dogs with non immune-mediated skin diseases. Direct immunofluorescence was seen in skin biopsy specimens maintained in Michel's medium for 4 to 8 years.
AB - Skin biopsy specimens from 7 dogs with immune-mediated skin diseases diagnosed by routine histology and 5 dogs with other skin diseases were placed in Michel's transport medium for 4 to 9 years. Direct immunofluorescence yielded positive results in tissue samples from 3 dogs with pemphigus foliaceus and 2 dogs with discoid lupus erythematosus. Direct immunofluorescence was not seen in tissue samples from 1 dog with pemphigus foliaceus and 5 dogs with non immune-mediated skin diseases. Direct immunofluorescence was seen in skin biopsy specimens maintained in Michel's medium for 4 to 8 years.
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U2 - 10.1016/0165-2427(85)90015-7
DO - 10.1016/0165-2427(85)90015-7
M3 - Article
C2 - 3898553
AN - SCOPUS:0021826394
VL - 9
SP - 161
EP - 170
JO - Veterinary Immunology and Immunopathology
JF - Veterinary Immunology and Immunopathology
SN - 0165-2427
IS - 2
ER -