The insulin and glucose response to an oral glucose load in non-insulin-dependent diabetes in the young. A study of 4 families

C. Naidoo, I. Jialal, T. Govender, M. A. Omar, S. M. Joubert

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Abstract

Four Indian families with three-generation transmission of non-insulin-dependent diabetes were studied. Only 30% of the siblings were diabetic. The mean age of onset of diabetes was 20,1 years; 25% of the diabetics were obese, while all non-diabetic family members were of normal weight. All consenting living family members (12 diabetics and 16 non-diabetics) were subjected to an oral glucose tolerance test. After glucose administration, the 12 diabetics displayed a delayed and attenuated insulinaemic response. The area under the insulin curve and the insulin-glucose ratio were lower in the diabetics.

Original languageEnglish (US)
Pages (from-to)119-121
Number of pages3
JournalSouth African Medical Journal
Volume69
Issue number2
StatePublished - 1986
Externally publishedYes

Fingerprint

Insulin
Glucose
Glucose Tolerance Test
Age of Onset
Area Under Curve
Siblings
Weights and Measures

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The insulin and glucose response to an oral glucose load in non-insulin-dependent diabetes in the young. A study of 4 families. / Naidoo, C.; Jialal, I.; Govender, T.; Omar, M. A.; Joubert, S. M.

In: South African Medical Journal, Vol. 69, No. 2, 1986, p. 119-121.

Research output: Contribution to journalArticle

Naidoo, C. ; Jialal, I. ; Govender, T. ; Omar, M. A. ; Joubert, S. M. / The insulin and glucose response to an oral glucose load in non-insulin-dependent diabetes in the young. A study of 4 families. In: South African Medical Journal. 1986 ; Vol. 69, No. 2. pp. 119-121.
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