The Influence of Thyroxine and Thiouracil on Rats Fed Excess Tyrosine (34572)

Amal M. Boctor; Quinton Rogers; A. E. Harper

doi:10.3181/00379727-133-34572

The Influence of Thyroxine and Thiouracil on Rats Fed Excess Tyrosine (34572)

Amal M. Boctor, Quinton Rogers, A. E. Harper

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Addition of thiouracil to a high tyrosine diet alleviated signs of tyrosine toxicity in the rat, whereas, daily injections of thyroxine aggravated them. Plasma tyrosine concentration and liver tyrosine transaminase activity were high in rats fed a high tyrosine diet; thyroxine administration increased them further, but depressed slightly the activity of liver p-hydroxyphenylpyruvate hydroxylase.

Original language	English (US)
Pages (from-to)	821-825
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	133
Issue number	3
DOIs	https://doi.org/10.3181/00379727-133-34572
State	Published - Jan 1 1970
Externally published	Yes

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ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Boctor, A. M., Rogers, Q., & Harper, A. E. (1970). The Influence of Thyroxine and Thiouracil on Rats Fed Excess Tyrosine (34572). Proceedings of the Society for Experimental Biology and Medicine, 133(3), 821-825. https://doi.org/10.3181/00379727-133-34572

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10.3181/00379727-133-34572