The Influence of Thyroxine and Thiouracil on Rats Fed Excess Tyrosine (34572)

Amal M. Boctor, Quinton Rogers, A. E. Harper

Research output: Contribution to journalArticle

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Abstract

Addition of thiouracil to a high tyrosine diet alleviated signs of tyrosine toxicity in the rat, whereas, daily injections of thyroxine aggravated them. Plasma tyrosine concentration and liver tyrosine transaminase activity were high in rats fed a high tyrosine diet; thyroxine administration increased them further, but depressed slightly the activity of liver p-hydroxyphenylpyruvate hydroxylase.

Original languageEnglish (US)
Pages (from-to)821-825
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume133
Issue number3
DOIs
StatePublished - Jan 1 1970
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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