Abstract
Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. Methods: Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. Results: African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao2/Fio2) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. Conclusions: Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 486-491 |
| Number of pages | 6 |
| Journal | American Journal of Surgery |
| Volume | 201 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2011 |
Fingerprint
Keywords
- Acute lung injury
- Acute respiratory distress syndrome
- Adult
- Epidemiology
- Race
- Trauma
ASJC Scopus subject areas
- Surgery
Cite this
The influence of race on the development of acute lung injury in trauma patients. / Brown, Lisa M; Kallet, Richard H.; Matthay, Michael A.; Dicker, Rochelle A.
In: American Journal of Surgery, Vol. 201, No. 4, 04.2011, p. 486-491.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The influence of race on the development of acute lung injury in trauma patients
AU - Brown, Lisa M
AU - Kallet, Richard H.
AU - Matthay, Michael A.
AU - Dicker, Rochelle A.
PY - 2011/4
Y1 - 2011/4
N2 - Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. Methods: Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. Results: African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao2/Fio2) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. Conclusions: Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.
AB - Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. Methods: Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. Results: African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao2/Fio2) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. Conclusions: Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.
KW - Acute lung injury
KW - Acute respiratory distress syndrome
KW - Adult
KW - Epidemiology
KW - Race
KW - Trauma
UR - http://www.scopus.com/inward/record.url?scp=79952988321&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952988321&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2010.02.003
DO - 10.1016/j.amjsurg.2010.02.003
M3 - Article
C2 - 20832050
AN - SCOPUS:79952988321
VL - 201
SP - 486
EP - 491
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 4
ER -