The influence of race on the development of acute lung injury in trauma patients

Lisa M Brown, Richard H. Kallet, Michael A. Matthay, Rochelle A. Dicker

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. Methods: Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. Results: African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao2/Fio2) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. Conclusions: Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.

Original languageEnglish (US)
Pages (from-to)486-491
Number of pages6
JournalAmerican Journal of Surgery
Volume201
Issue number4
DOIs
StatePublished - Apr 2011

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Acute Lung Injury
Adult Respiratory Distress Syndrome
Lung Injury
Wounds and Injuries
African Americans
Mortality
Oxygen
Partial Pressure
Trauma Centers
Incidence
Hispanic Americans
Intensive Care Units
Shock
Cohort Studies
Retrospective Studies

Keywords

  • Acute lung injury
  • Acute respiratory distress syndrome
  • Adult
  • Epidemiology
  • Race
  • Trauma

ASJC Scopus subject areas

  • Surgery

Cite this

The influence of race on the development of acute lung injury in trauma patients. / Brown, Lisa M; Kallet, Richard H.; Matthay, Michael A.; Dicker, Rochelle A.

In: American Journal of Surgery, Vol. 201, No. 4, 04.2011, p. 486-491.

Research output: Contribution to journalArticle

Brown, Lisa M ; Kallet, Richard H. ; Matthay, Michael A. ; Dicker, Rochelle A. / The influence of race on the development of acute lung injury in trauma patients. In: American Journal of Surgery. 2011 ; Vol. 201, No. 4. pp. 486-491.
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