The influence of race on the development of acute lung injury in trauma patients

Lisa M Brown, Richard H. Kallet, Michael A. Matthay, Rochelle A. Dicker

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. Methods: Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. Results: African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao2/Fio2) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. Conclusions: Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.

Original languageEnglish (US)
Pages (from-to)486-491
Number of pages6
JournalAmerican Journal of Surgery
Issue number4
StatePublished - Apr 2011


  • Acute lung injury
  • Acute respiratory distress syndrome
  • Adult
  • Epidemiology
  • Race
  • Trauma

ASJC Scopus subject areas

  • Surgery


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