The incidence of traumatic intracranial hemorrhage in head-injured older adults transported by EMS with and without anticoagulant or antiplatelet use

Daniel Nishijima, Samuel D. Gaona, Trent Waechter, Ric Maloney, Adam Blitz, Andrew R. Elms, Roel D. Farrales, James Montoya, Troy Bair, Calvin Howard, Megan Gilbert, Renee P. Trajano, Kaela M. Hatchel, Mark Faul, Jeneita M. Bell, Victor C. Coronado, David R. Vinson, Dustin W. Ballard, Daniel J Tancredi, Hernando GarzonKevin E. Mackey, Kiarash Shahlaie, James F Holmes Jr

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Field triage guidelines recommend transport of head-injured patients on anticoagulants or antiplatelets to a higher-level trauma center based on studies suggesting a high incidence of traumatic intracranial hemorrhage (tICH). We compared the incidence of tICH in older adults transported by emergency medical services (EMS) with and without anticoagulation or antiplatelet use and evaluated the accuracies of different sets of field triage criteria to identify tICH. This was a prospective, observational study at five EMS agencies and 11 hospitals. Older adults (≥55 years) with head trauma and transported by EMS from August 2015 to September 2016 were eligible. EMS providers completed standardized data forms and patients were followed through emergency department (ED) or hospital discharge. We enrolled 1304 patients; 1147 (88%) received a cranial computed tomography (CT) scan and were eligible for analysis. Four hundred thirty-four (33%) patients had anticoagulant or antiplatelet use and 112 (10%) had tICH. The incidence of tICH in patients with (11%, 95% confidence interval [CI] 8%-14%) and without (9%, 95% CI 7%-11%) anticoagulant or antiplatelet use was similar. Anticoagulant or antiplatelet use was not predictive of tICH on adjusted analysis. Steps 1-3 criteria alone were not sensitive in identifying tICH (27%), whereas the addition of anticoagulant or antiplatelet criterion improved sensitivity (63%). Other derived sets of triage criteria were highly sensitive (>98%) but poorly specific (<11%). The incidence of tICH was similar between patients with and without anticoagulant or antiplatelet use. Use of anticoagulant or antiplatelet medications was not a risk factor for tICH. We were unable to identify a set of triage criteria that was accurate for trauma center need.

Original languageEnglish (US)
Pages (from-to)750-759
Number of pages10
JournalJournal of Neurotrauma
Volume35
Issue number5
DOIs
StatePublished - Mar 1 2018

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Traumatic Intracranial Hemorrhage
Emergency Medical Services
Anticoagulants
Head
Incidence
Triage
Trauma Centers
Confidence Intervals
Craniocerebral Trauma
Observational Studies
Hospital Emergency Service
Tomography

Keywords

  • anticoagulants
  • field triage
  • head injuries
  • older adults

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

The incidence of traumatic intracranial hemorrhage in head-injured older adults transported by EMS with and without anticoagulant or antiplatelet use. / Nishijima, Daniel; Gaona, Samuel D.; Waechter, Trent; Maloney, Ric; Blitz, Adam; Elms, Andrew R.; Farrales, Roel D.; Montoya, James; Bair, Troy; Howard, Calvin; Gilbert, Megan; Trajano, Renee P.; Hatchel, Kaela M.; Faul, Mark; Bell, Jeneita M.; Coronado, Victor C.; Vinson, David R.; Ballard, Dustin W.; Tancredi, Daniel J; Garzon, Hernando; Mackey, Kevin E.; Shahlaie, Kiarash; Holmes Jr, James F.

In: Journal of Neurotrauma, Vol. 35, No. 5, 01.03.2018, p. 750-759.

Research output: Contribution to journalArticle

Nishijima, D, Gaona, SD, Waechter, T, Maloney, R, Blitz, A, Elms, AR, Farrales, RD, Montoya, J, Bair, T, Howard, C, Gilbert, M, Trajano, RP, Hatchel, KM, Faul, M, Bell, JM, Coronado, VC, Vinson, DR, Ballard, DW, Tancredi, DJ, Garzon, H, Mackey, KE, Shahlaie, K & Holmes Jr, JF 2018, 'The incidence of traumatic intracranial hemorrhage in head-injured older adults transported by EMS with and without anticoagulant or antiplatelet use', Journal of Neurotrauma, vol. 35, no. 5, pp. 750-759. https://doi.org/10.1089/neu.2017.5232
Nishijima, Daniel ; Gaona, Samuel D. ; Waechter, Trent ; Maloney, Ric ; Blitz, Adam ; Elms, Andrew R. ; Farrales, Roel D. ; Montoya, James ; Bair, Troy ; Howard, Calvin ; Gilbert, Megan ; Trajano, Renee P. ; Hatchel, Kaela M. ; Faul, Mark ; Bell, Jeneita M. ; Coronado, Victor C. ; Vinson, David R. ; Ballard, Dustin W. ; Tancredi, Daniel J ; Garzon, Hernando ; Mackey, Kevin E. ; Shahlaie, Kiarash ; Holmes Jr, James F. / The incidence of traumatic intracranial hemorrhage in head-injured older adults transported by EMS with and without anticoagulant or antiplatelet use. In: Journal of Neurotrauma. 2018 ; Vol. 35, No. 5. pp. 750-759.
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AU - Blitz, Adam

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