The incidence of systemic lupus erythematosus in North American Indians.

R. O. Morton, M. Eric Gershwin, C. Brady, A. D. Steinberg

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The annual incidence (AI) of systemic lupus erythematosus (SLE) was determined in 75 highly inbred North American Indian tribes, a total of approximately 800,000 people, during the fiscal years 1971-1975. Seventy-two of the Indian tribes had an AI of SLE which was of similar magnitude to previously published studies from Sweden, Rochester (Minn.), Alabama, New York City, and San Francisco. However, Three tribes, the Crow, Arapahoe, and Sioux Indians, had a markedly elevated AI of SLE. These three tribes share common historical, geographic, and cultural characteristics. Further, they all reside in the northern half of the United States, in states that do not receive intense sun exposure, thereby eliminating photosensitivity as a major determinant of this increased prevalence. Finally, the AI of SLE in the Sioux Indians was highest for "full-blooded" members and lowest for genetic admixtures.

Original languageEnglish (US)
Pages (from-to)186-190
Number of pages5
JournalJournal of Rheumatology
Volume3
Issue number2
StatePublished - Jun 1976
Externally publishedYes

Fingerprint

North American Indians
Population Groups
Systemic Lupus Erythematosus
Incidence
Cultural Characteristics
Crows
San Francisco
Solar System
Sweden

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

The incidence of systemic lupus erythematosus in North American Indians. / Morton, R. O.; Gershwin, M. Eric; Brady, C.; Steinberg, A. D.

In: Journal of Rheumatology, Vol. 3, No. 2, 06.1976, p. 186-190.

Research output: Contribution to journalArticle

Morton, RO, Gershwin, ME, Brady, C & Steinberg, AD 1976, 'The incidence of systemic lupus erythematosus in North American Indians.', Journal of Rheumatology, vol. 3, no. 2, pp. 186-190.
Morton, R. O. ; Gershwin, M. Eric ; Brady, C. ; Steinberg, A. D. / The incidence of systemic lupus erythematosus in North American Indians. In: Journal of Rheumatology. 1976 ; Vol. 3, No. 2. pp. 186-190.
@article{22ebe69ba0d046f88316a99862e468a6,
title = "The incidence of systemic lupus erythematosus in North American Indians.",
abstract = "The annual incidence (AI) of systemic lupus erythematosus (SLE) was determined in 75 highly inbred North American Indian tribes, a total of approximately 800,000 people, during the fiscal years 1971-1975. Seventy-two of the Indian tribes had an AI of SLE which was of similar magnitude to previously published studies from Sweden, Rochester (Minn.), Alabama, New York City, and San Francisco. However, Three tribes, the Crow, Arapahoe, and Sioux Indians, had a markedly elevated AI of SLE. These three tribes share common historical, geographic, and cultural characteristics. Further, they all reside in the northern half of the United States, in states that do not receive intense sun exposure, thereby eliminating photosensitivity as a major determinant of this increased prevalence. Finally, the AI of SLE in the Sioux Indians was highest for {"}full-blooded{"} members and lowest for genetic admixtures.",
author = "Morton, {R. O.} and Gershwin, {M. Eric} and C. Brady and Steinberg, {A. D.}",
year = "1976",
month = "6",
language = "English (US)",
volume = "3",
pages = "186--190",
journal = "Journal of Rheumatology",
issn = "0315-162X",
publisher = "Journal of Rheumatology",
number = "2",

}

TY - JOUR

T1 - The incidence of systemic lupus erythematosus in North American Indians.

AU - Morton, R. O.

AU - Gershwin, M. Eric

AU - Brady, C.

AU - Steinberg, A. D.

PY - 1976/6

Y1 - 1976/6

N2 - The annual incidence (AI) of systemic lupus erythematosus (SLE) was determined in 75 highly inbred North American Indian tribes, a total of approximately 800,000 people, during the fiscal years 1971-1975. Seventy-two of the Indian tribes had an AI of SLE which was of similar magnitude to previously published studies from Sweden, Rochester (Minn.), Alabama, New York City, and San Francisco. However, Three tribes, the Crow, Arapahoe, and Sioux Indians, had a markedly elevated AI of SLE. These three tribes share common historical, geographic, and cultural characteristics. Further, they all reside in the northern half of the United States, in states that do not receive intense sun exposure, thereby eliminating photosensitivity as a major determinant of this increased prevalence. Finally, the AI of SLE in the Sioux Indians was highest for "full-blooded" members and lowest for genetic admixtures.

AB - The annual incidence (AI) of systemic lupus erythematosus (SLE) was determined in 75 highly inbred North American Indian tribes, a total of approximately 800,000 people, during the fiscal years 1971-1975. Seventy-two of the Indian tribes had an AI of SLE which was of similar magnitude to previously published studies from Sweden, Rochester (Minn.), Alabama, New York City, and San Francisco. However, Three tribes, the Crow, Arapahoe, and Sioux Indians, had a markedly elevated AI of SLE. These three tribes share common historical, geographic, and cultural characteristics. Further, they all reside in the northern half of the United States, in states that do not receive intense sun exposure, thereby eliminating photosensitivity as a major determinant of this increased prevalence. Finally, the AI of SLE in the Sioux Indians was highest for "full-blooded" members and lowest for genetic admixtures.

UR - http://www.scopus.com/inward/record.url?scp=0016970654&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016970654&partnerID=8YFLogxK

M3 - Article

C2 - 950634

AN - SCOPUS:0016970654

VL - 3

SP - 186

EP - 190

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

IS - 2

ER -