The Importance of Dispensable Amino Acids for Maximal Growth in the Rat

Quinton Rogers, D. M.Y. Chen, A. E. Harper

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Various quantities of dispensable amino acids have been fed to rats in an attempt to determine what combination is best for maximal growth. The quantity of one dispensable amino acid that was necessary for maximal growth has been shown to depend upon the quantity of one or more other dispensable amino acids. In fact, individual groups of rats which were fed diets that were devoid of one of the following: glutamic acid, proline, aspartic acid, and asparagine, alanine, serine, or glutamine and glutamic acid, grew maximally. Thus, no minimal requirements could be established for the above amino acids. However, a minimal requirement for arginine was found to be about 0.3% of the diet even when proline and glutamic acid were both added in excess.

Original languageEnglish (US)
Pages (from-to)517-522
Number of pages6
JournalProceedings of the Society for Experimental Biology and Medicine
Volume134
Issue number2
DOIs
StatePublished - Jan 1 1970

Fingerprint

Rats
Amino Acids
Glutamic Acid
Nutrition
Growth
Proline
Diet
Asparagine
Glutamine
Aspartic Acid
Alanine
Serine
Arginine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

The Importance of Dispensable Amino Acids for Maximal Growth in the Rat. / Rogers, Quinton; Chen, D. M.Y.; Harper, A. E.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 134, No. 2, 01.01.1970, p. 517-522.

Research output: Contribution to journalArticle

@article{f5ddfa9b26184a17bfceb3351d08311a,
title = "The Importance of Dispensable Amino Acids for Maximal Growth in the Rat",
abstract = "Various quantities of dispensable amino acids have been fed to rats in an attempt to determine what combination is best for maximal growth. The quantity of one dispensable amino acid that was necessary for maximal growth has been shown to depend upon the quantity of one or more other dispensable amino acids. In fact, individual groups of rats which were fed diets that were devoid of one of the following: glutamic acid, proline, aspartic acid, and asparagine, alanine, serine, or glutamine and glutamic acid, grew maximally. Thus, no minimal requirements could be established for the above amino acids. However, a minimal requirement for arginine was found to be about 0.3{\%} of the diet even when proline and glutamic acid were both added in excess.",
author = "Quinton Rogers and Chen, {D. M.Y.} and Harper, {A. E.}",
year = "1970",
month = "1",
day = "1",
doi = "10.3181/00379727-134-34826",
language = "English (US)",
volume = "134",
pages = "517--522",
journal = "Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)",
issn = "1535-3702",
publisher = "Society for Experimental Biology and Medicine",
number = "2",

}

TY - JOUR

T1 - The Importance of Dispensable Amino Acids for Maximal Growth in the Rat

AU - Rogers, Quinton

AU - Chen, D. M.Y.

AU - Harper, A. E.

PY - 1970/1/1

Y1 - 1970/1/1

N2 - Various quantities of dispensable amino acids have been fed to rats in an attempt to determine what combination is best for maximal growth. The quantity of one dispensable amino acid that was necessary for maximal growth has been shown to depend upon the quantity of one or more other dispensable amino acids. In fact, individual groups of rats which were fed diets that were devoid of one of the following: glutamic acid, proline, aspartic acid, and asparagine, alanine, serine, or glutamine and glutamic acid, grew maximally. Thus, no minimal requirements could be established for the above amino acids. However, a minimal requirement for arginine was found to be about 0.3% of the diet even when proline and glutamic acid were both added in excess.

AB - Various quantities of dispensable amino acids have been fed to rats in an attempt to determine what combination is best for maximal growth. The quantity of one dispensable amino acid that was necessary for maximal growth has been shown to depend upon the quantity of one or more other dispensable amino acids. In fact, individual groups of rats which were fed diets that were devoid of one of the following: glutamic acid, proline, aspartic acid, and asparagine, alanine, serine, or glutamine and glutamic acid, grew maximally. Thus, no minimal requirements could be established for the above amino acids. However, a minimal requirement for arginine was found to be about 0.3% of the diet even when proline and glutamic acid were both added in excess.

UR - http://www.scopus.com/inward/record.url?scp=0014803574&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014803574&partnerID=8YFLogxK

U2 - 10.3181/00379727-134-34826

DO - 10.3181/00379727-134-34826

M3 - Article

C2 - 5419140

AN - SCOPUS:0014803574

VL - 134

SP - 517

EP - 522

JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

SN - 1535-3702

IS - 2

ER -