The impact of animal age, bacterial coinfection, and isolate pathogenicity on the shedding of Porcine reproductive and respiratory syndrome virus in aerosols from experimentally infected pigs

Jenny G. Cho, Scott A. Dee, John Deen, Carlos Trincado, Eduardo Fano, Yin Jiang, Kay Faaberg, Michael P. Murtaugh, Alonso Guedes, James E. Collins, Han Soo Joo

Research output: Contribution to journalArticle

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Abstract

The objective of this study was to evaluate the role of different variables (animal age, bacterial coinfection, and isolate pathogenicity) on the shedding of Porcine reproductive and respiratory syndrome virus (PRRSV) in aerosols. Animals were grouped according to age (2 versus 6 mo) and inoculated with a PRRSV isolate of either low (MN-30100) or high (MN-184) pathogenicity. Selected animals in each group were also inoculated with Mycoplasma hyopneumoniae. The pigs were anesthetized and aerosol samples (1000 breaths/sample) collected on alternating days from 1 to 21 after PRRSV inoculation. The results indicated that animal age (P = 0.09), M. hyopneumoniae coinfection (P = 0.09), and PRRSV isolate pathogenicity (P = 0.15) did not significantly influence the concentration of PRRSV in aerosols. However, inoculation with the PRRSV MN-184 isolate significantly increased the probability of aerosol shedding (P = 0.00005; odds ratio = 3.22). Therefore, the shedding of PRRSV in aerosols may be isolate-dependent.

Original languageEnglish (US)
Pages (from-to)297-301
Number of pages5
JournalCanadian Journal of Veterinary Research
Volume70
Issue number4
StatePublished - Oct 2006
Externally publishedYes

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Porcine respiratory and reproductive syndrome virus
Porcine reproductive and respiratory syndrome virus
animal age
aerosols
Aerosols
Coinfection
mixed infection
Virulence
Swine
pathogenicity
swine
Mycoplasma hyopneumoniae
odds ratio
animals
Odds Ratio
sampling

ASJC Scopus subject areas

  • veterinary(all)

Cite this

The impact of animal age, bacterial coinfection, and isolate pathogenicity on the shedding of Porcine reproductive and respiratory syndrome virus in aerosols from experimentally infected pigs. / Cho, Jenny G.; Dee, Scott A.; Deen, John; Trincado, Carlos; Fano, Eduardo; Jiang, Yin; Faaberg, Kay; Murtaugh, Michael P.; Guedes, Alonso; Collins, James E.; Joo, Han Soo.

In: Canadian Journal of Veterinary Research, Vol. 70, No. 4, 10.2006, p. 297-301.

Research output: Contribution to journalArticle

Cho, JG, Dee, SA, Deen, J, Trincado, C, Fano, E, Jiang, Y, Faaberg, K, Murtaugh, MP, Guedes, A, Collins, JE & Joo, HS 2006, 'The impact of animal age, bacterial coinfection, and isolate pathogenicity on the shedding of Porcine reproductive and respiratory syndrome virus in aerosols from experimentally infected pigs', Canadian Journal of Veterinary Research, vol. 70, no. 4, pp. 297-301.
Cho, Jenny G. ; Dee, Scott A. ; Deen, John ; Trincado, Carlos ; Fano, Eduardo ; Jiang, Yin ; Faaberg, Kay ; Murtaugh, Michael P. ; Guedes, Alonso ; Collins, James E. ; Joo, Han Soo. / The impact of animal age, bacterial coinfection, and isolate pathogenicity on the shedding of Porcine reproductive and respiratory syndrome virus in aerosols from experimentally infected pigs. In: Canadian Journal of Veterinary Research. 2006 ; Vol. 70, No. 4. pp. 297-301.
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