Abstract
The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (>50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (>100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 235-237 |
| Number of pages | 3 |
| Journal | Journal of Endocrinological Investigation |
| Volume | 7 |
| Issue number | 3 |
| State | Published - 1984 |
| Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology
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Jialal, I., Naidoo, C., Nathoo, B. C., Rajput, M. C., & Joubert, S. M. (1984). The growth hormone responses to L-dopa and TRH in acromegaly. Journal of Endocrinological Investigation, 7(3), 235-237.