The growth hormone responses to L-dopa and TRH in acromegaly

I. Jialal; C. Naidoo; B. C. Nathoo; M. C. Rajput; S. M. Joubert

The growth hormone responses to L-dopa and TRH in acromegaly

I. Jialal, C. Naidoo, B. C. Nathoo, M. C. Rajput, S. M. Joubert

Research output: Contribution to journal › Article › peer-review

Abstract

The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (>50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (>100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.

Original language	English (US)
Pages (from-to)	235-237
Number of pages	3
Journal	Journal of Endocrinological Investigation
Volume	7
Issue number	3
State	Published - 1984
Externally published	Yes

ASJC Scopus subject areas

Endocrinology

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abstract = "The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (>50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (>100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.",

author = "I. Jialal and C. Naidoo and Nathoo, {B. C.} and Rajput, {M. C.} and Joubert, {S. M.}",

year = "1984",

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AU - Jialal, I.

AU - Naidoo, C.

AU - Nathoo, B. C.

AU - Rajput, M. C.

AU - Joubert, S. M.

PY - 1984

Y1 - 1984

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AB - The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (>50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (>100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.

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JO - Journal of Endocrinological Investigation

JF - Journal of Endocrinological Investigation

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The growth hormone responses to L-dopa and TRH in acromegaly

Abstract

ASJC Scopus subject areas

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