The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (>50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (>100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Endocrinological Investigation|
|State||Published - 1984|
ASJC Scopus subject areas