The genome of the natural genetic engineer Agrobacterium tumefaciens C58

D. W. Wood, J. C. Setubal, R. Kaul, D. E. Monks, J. P. Kitajima, V. K. Okura, Y. Zhou, L. Chen, G. E. Wood, Jr Almeida N.F., L. Woo, Y. Chen, I. T. Paulsen, Jonathan A Eisen, P. D. Karp, Sr Bovee D., P. Chapman, J. Clendenning, G. Deatherage, W. GilletC. Grant, T. Kutyavin, R. Levy, M. J. Li, E. McClelland, A. Palmieri, C. Raymond, G. Rouse, C. Saenphimmachak, Z. Wu, P. Romero, D. Gordon, S. Zhang, H. Yoo, Y. Tao, P. Biddle, M. Jung, W. Krespan, M. Perry, B. Gordon-Kamm, L. Liao, S. Kim, C. Hendrick, Z. Y. Zhao, M. Dolan, F. Chumley, S. V. Tingey, J. F. Tomb, M. P. Gordon, M. V. Olson, E. W. Nester

Research output: Contribution to journalArticle

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Abstract

The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include metabolic, transport, and regulatory systems that promote survival in the highly competitive rhizosphere; differences are apparent in their genome structure and virulence gene complement. Availability of the A. tumefaciens sequence will facilitate investigations into the molecular basis of pathogenesis and the evolutionary divergence of pathogenic and symbiotic lifestyles.

Original languageEnglish (US)
Pages (from-to)2317-2323
Number of pages7
JournalScience
Volume294
Issue number5550
DOIs
StatePublished - Dec 14 2001
Externally publishedYes

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Agrobacterium tumefaciens
Genome
Chromosomes
Sinorhizobium meliloti
Plant Genome
Rhizosphere
Virulence
Life Style
Plasmids
Nucleotides
Genes

ASJC Scopus subject areas

  • General

Cite this

Wood, D. W., Setubal, J. C., Kaul, R., Monks, D. E., Kitajima, J. P., Okura, V. K., ... Nester, E. W. (2001). The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science, 294(5550), 2317-2323. https://doi.org/10.1126/science.1066804

The genome of the natural genetic engineer Agrobacterium tumefaciens C58. / Wood, D. W.; Setubal, J. C.; Kaul, R.; Monks, D. E.; Kitajima, J. P.; Okura, V. K.; Zhou, Y.; Chen, L.; Wood, G. E.; Almeida N.F., Jr; Woo, L.; Chen, Y.; Paulsen, I. T.; Eisen, Jonathan A; Karp, P. D.; Bovee D., Sr; Chapman, P.; Clendenning, J.; Deatherage, G.; Gillet, W.; Grant, C.; Kutyavin, T.; Levy, R.; Li, M. J.; McClelland, E.; Palmieri, A.; Raymond, C.; Rouse, G.; Saenphimmachak, C.; Wu, Z.; Romero, P.; Gordon, D.; Zhang, S.; Yoo, H.; Tao, Y.; Biddle, P.; Jung, M.; Krespan, W.; Perry, M.; Gordon-Kamm, B.; Liao, L.; Kim, S.; Hendrick, C.; Zhao, Z. Y.; Dolan, M.; Chumley, F.; Tingey, S. V.; Tomb, J. F.; Gordon, M. P.; Olson, M. V.; Nester, E. W.

In: Science, Vol. 294, No. 5550, 14.12.2001, p. 2317-2323.

Research output: Contribution to journalArticle

Wood, DW, Setubal, JC, Kaul, R, Monks, DE, Kitajima, JP, Okura, VK, Zhou, Y, Chen, L, Wood, GE, Almeida N.F., J, Woo, L, Chen, Y, Paulsen, IT, Eisen, JA, Karp, PD, Bovee D., S, Chapman, P, Clendenning, J, Deatherage, G, Gillet, W, Grant, C, Kutyavin, T, Levy, R, Li, MJ, McClelland, E, Palmieri, A, Raymond, C, Rouse, G, Saenphimmachak, C, Wu, Z, Romero, P, Gordon, D, Zhang, S, Yoo, H, Tao, Y, Biddle, P, Jung, M, Krespan, W, Perry, M, Gordon-Kamm, B, Liao, L, Kim, S, Hendrick, C, Zhao, ZY, Dolan, M, Chumley, F, Tingey, SV, Tomb, JF, Gordon, MP, Olson, MV & Nester, EW 2001, 'The genome of the natural genetic engineer Agrobacterium tumefaciens C58', Science, vol. 294, no. 5550, pp. 2317-2323. https://doi.org/10.1126/science.1066804
Wood DW, Setubal JC, Kaul R, Monks DE, Kitajima JP, Okura VK et al. The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science. 2001 Dec 14;294(5550):2317-2323. https://doi.org/10.1126/science.1066804
Wood, D. W. ; Setubal, J. C. ; Kaul, R. ; Monks, D. E. ; Kitajima, J. P. ; Okura, V. K. ; Zhou, Y. ; Chen, L. ; Wood, G. E. ; Almeida N.F., Jr ; Woo, L. ; Chen, Y. ; Paulsen, I. T. ; Eisen, Jonathan A ; Karp, P. D. ; Bovee D., Sr ; Chapman, P. ; Clendenning, J. ; Deatherage, G. ; Gillet, W. ; Grant, C. ; Kutyavin, T. ; Levy, R. ; Li, M. J. ; McClelland, E. ; Palmieri, A. ; Raymond, C. ; Rouse, G. ; Saenphimmachak, C. ; Wu, Z. ; Romero, P. ; Gordon, D. ; Zhang, S. ; Yoo, H. ; Tao, Y. ; Biddle, P. ; Jung, M. ; Krespan, W. ; Perry, M. ; Gordon-Kamm, B. ; Liao, L. ; Kim, S. ; Hendrick, C. ; Zhao, Z. Y. ; Dolan, M. ; Chumley, F. ; Tingey, S. V. ; Tomb, J. F. ; Gordon, M. P. ; Olson, M. V. ; Nester, E. W. / The genome of the natural genetic engineer Agrobacterium tumefaciens C58. In: Science. 2001 ; Vol. 294, No. 5550. pp. 2317-2323.
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AU - Wood, D. W.

AU - Setubal, J. C.

AU - Kaul, R.

AU - Monks, D. E.

AU - Kitajima, J. P.

AU - Okura, V. K.

AU - Zhou, Y.

AU - Chen, L.

AU - Wood, G. E.

AU - Almeida N.F., Jr

AU - Woo, L.

AU - Chen, Y.

AU - Paulsen, I. T.

AU - Eisen, Jonathan A

AU - Karp, P. D.

AU - Bovee D., Sr

AU - Chapman, P.

AU - Clendenning, J.

AU - Deatherage, G.

AU - Gillet, W.

AU - Grant, C.

AU - Kutyavin, T.

AU - Levy, R.

AU - Li, M. J.

AU - McClelland, E.

AU - Palmieri, A.

AU - Raymond, C.

AU - Rouse, G.

AU - Saenphimmachak, C.

AU - Wu, Z.

AU - Romero, P.

AU - Gordon, D.

AU - Zhang, S.

AU - Yoo, H.

AU - Tao, Y.

AU - Biddle, P.

AU - Jung, M.

AU - Krespan, W.

AU - Perry, M.

AU - Gordon-Kamm, B.

AU - Liao, L.

AU - Kim, S.

AU - Hendrick, C.

AU - Zhao, Z. Y.

AU - Dolan, M.

AU - Chumley, F.

AU - Tingey, S. V.

AU - Tomb, J. F.

AU - Gordon, M. P.

AU - Olson, M. V.

AU - Nester, E. W.

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