The gas-phase chemistry of cyclodextrin inclusion complexes

Carlito B Lebrilla

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Complexes of cyclodextrins with amino acid analytes are produced in the gas phase and are ideal for the study of molecular recognition. In this Account, we discuss the evidence for the presence of gas-phase inclusion complexes and the nature of the interaction. The use of cyclodextrins as chiral selectors in gas-phase guest-exchange reactions is illustrated, and the nature of the enantioselectivity is discussed. The development of the enantioselective reaction into an analytical method for determining enantiomeric excess is also described.

Original languageEnglish (US)
Pages (from-to)653-661
Number of pages9
JournalAccounts of Chemical Research
Volume34
Issue number8
DOIs
StatePublished - 2001

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Cyclodextrins
Gases
Molecular recognition
Enantioselectivity
Amino Acids

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

The gas-phase chemistry of cyclodextrin inclusion complexes. / Lebrilla, Carlito B.

In: Accounts of Chemical Research, Vol. 34, No. 8, 2001, p. 653-661.

Research output: Contribution to journalArticle

Lebrilla, Carlito B. / The gas-phase chemistry of cyclodextrin inclusion complexes. In: Accounts of Chemical Research. 2001 ; Vol. 34, No. 8. pp. 653-661.
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