Abstract
The teneurins are a family of four transmembrane proteins expressed in the developing vertebrate nervous system, though the Drosophila teneurin ten-m is also a pair-rule gene. Whole-mount in situ hybridization was used to localize teneurin-4 transcripts in the chicken embryo. The earliest signal is detected at stage 19 in the somites and limb buds. By stage 20 teneurin-4 transcripts are detected in temporal periocular mesenchyme, branchial arches, diencephalon and somites. Teneurin-4 expression in the limbs changes dramatically during development. Between stages 19 and 21 teneurin-4 expression is concentrated proximally in the zone of polarizing activity. Between stages 24 and 26 teneurin-4 is expressed in the mesenchyme of the anterodistal part of the limb. As in Drosophila, vertebrate teneurins are expressed not only in the nervous system, but also in non-neuronal tissues during pattern formation. Copyright (C) 2000 Elsevier Science Ireland Ltd.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 187-191 |
| Number of pages | 5 |
| Journal | Mechanisms of Development |
| Volume | 98 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Nov 1 2000 |
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Keywords
- Chick embryo
- DOC4
- In situ hybridization
- Limb development
- Morphogenesis
- Neurestin
- Odz
- Somite
- ten-a
- ten-m
- Teneurin-1
ASJC Scopus subject areas
- Developmental Biology
- Developmental Neuroscience
Cite this
The expression of teneurin-4 in the avian embryo. / Tucker, Richard P; Martin, Doris; Kos, Robert; Chiquet-Ehrismann, Ruth.
In: Mechanisms of Development, Vol. 98, No. 1-2, 01.11.2000, p. 187-191.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The expression of teneurin-4 in the avian embryo
AU - Tucker, Richard P
AU - Martin, Doris
AU - Kos, Robert
AU - Chiquet-Ehrismann, Ruth
PY - 2000/11/1
Y1 - 2000/11/1
N2 - The teneurins are a family of four transmembrane proteins expressed in the developing vertebrate nervous system, though the Drosophila teneurin ten-m is also a pair-rule gene. Whole-mount in situ hybridization was used to localize teneurin-4 transcripts in the chicken embryo. The earliest signal is detected at stage 19 in the somites and limb buds. By stage 20 teneurin-4 transcripts are detected in temporal periocular mesenchyme, branchial arches, diencephalon and somites. Teneurin-4 expression in the limbs changes dramatically during development. Between stages 19 and 21 teneurin-4 expression is concentrated proximally in the zone of polarizing activity. Between stages 24 and 26 teneurin-4 is expressed in the mesenchyme of the anterodistal part of the limb. As in Drosophila, vertebrate teneurins are expressed not only in the nervous system, but also in non-neuronal tissues during pattern formation. Copyright (C) 2000 Elsevier Science Ireland Ltd.
AB - The teneurins are a family of four transmembrane proteins expressed in the developing vertebrate nervous system, though the Drosophila teneurin ten-m is also a pair-rule gene. Whole-mount in situ hybridization was used to localize teneurin-4 transcripts in the chicken embryo. The earliest signal is detected at stage 19 in the somites and limb buds. By stage 20 teneurin-4 transcripts are detected in temporal periocular mesenchyme, branchial arches, diencephalon and somites. Teneurin-4 expression in the limbs changes dramatically during development. Between stages 19 and 21 teneurin-4 expression is concentrated proximally in the zone of polarizing activity. Between stages 24 and 26 teneurin-4 is expressed in the mesenchyme of the anterodistal part of the limb. As in Drosophila, vertebrate teneurins are expressed not only in the nervous system, but also in non-neuronal tissues during pattern formation. Copyright (C) 2000 Elsevier Science Ireland Ltd.
KW - Chick embryo
KW - DOC4
KW - In situ hybridization
KW - Limb development
KW - Morphogenesis
KW - Neurestin
KW - Odz
KW - Somite
KW - ten-a
KW - ten-m
KW - Teneurin-1
UR - http://www.scopus.com/inward/record.url?scp=0034333502&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034333502&partnerID=8YFLogxK
U2 - 10.1016/S0925-4773(00)00444-5
DO - 10.1016/S0925-4773(00)00444-5
M3 - Article
VL - 98
SP - 187
EP - 191
JO - Mechanisms of Development
JF - Mechanisms of Development
SN - 0925-4773
IS - 1-2
ER -