The evolution of peroxisomal and mitochondrial alanine: Glyoxylate aminotransferase 1 in mammalian liver

Yoshikazu Takada, Tomoo Noguchi

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Immunological distances of alanine: glyoxylate aminotransferase 1 (serine:pyruvate aminotransferase) in mitochondria or peroxisomes from eight different mammalian liver were determined with rabbit anti-serum against the mitochondrial enzyme of rat liver by microcomplement fixation. Results suggest that heterotopic alanine:glyoxylate aminotransferase 1 are orthologous proteins and their subcellular localization and substrate specificity changed during rapid molecular evolution.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume108
Issue number1
DOIs
StatePublished - Sep 16 1982
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this