The evaluation of anti juvenile hormones using last stadium larvae of the cabbage looper, Trichoplusia ni (Hübner)

Thomas C. Sparks, R. Michael Roe, Adrian Buehler, Bruce D. Hammock

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Treatment of prepupae of the cabbage looper, Trichoplusia ni (Hübner), with the anti juvenile hormone (AJH) fluoromevalonolactone (FMev) reduces juvenile hormone esterase (JHE) activity and either delays or inhibits the normal larval-pupal ecdysis in a dose-dependent manner, resulting in the formation of pupae with a suite of characteristic abnormalities. A variety of putative AJHs were evaluated using these teratogenic effects and changes in JHE activity as indicators of AJH activity. Like FMev, the compactin analog L-643,049-01K01 and, at very high doses, 3,3-dichloro-2-propenyl hexanoate (DPH) behaved as AJHs. FMev and L-643,049-01K01 were most effective when larvae were treated at gut purge, while DPH was the most effective after the initiation of spinning behavior.

Original languageEnglish (US)
Pages (from-to)1011-1016
Number of pages6
JournalInsect Biochemistry
Volume17
Issue number7
DOIs
StatePublished - 1987

Keywords

  • anti juvenile hormone
  • juvenile hormone
  • juvenile hormone esterase
  • Trichoplusia ni

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