The etiology of transmissible murine colonic hyperplasia

Stephen W Barthold, G. L. Coleman, P. N. Bhatt, G. W. Osbaldiston, A. M. Jonas

Research output: Chapter in Book/Report/Conference proceedingChapter

86 Citations (Scopus)

Abstract

The etiology of a transmissible colonic mucosal hyperplasia of mice was investigated. Hyperplasia was produced in mice inoculated with unfiltered colonic suspension from affected mice, but infectivity was lost after passage through a 0.45 μm filter. The etiologic agent was subsequently identified as a variant of Citrobacter freundii. The organism induced colonic mucosal hyperplasia when inoculated into germfree mice, and it was recovered in pure culture from the affected animals.

Original languageEnglish (US)
Title of host publicationLaboratory Animal Science
Volume26
Edition6
StatePublished - 1976
Externally publishedYes

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Hyperplasia
Citrobacter freundii
Suspensions

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Barthold, S. W., Coleman, G. L., Bhatt, P. N., Osbaldiston, G. W., & Jonas, A. M. (1976). The etiology of transmissible murine colonic hyperplasia. In Laboratory Animal Science (6 ed., Vol. 26)

The etiology of transmissible murine colonic hyperplasia. / Barthold, Stephen W; Coleman, G. L.; Bhatt, P. N.; Osbaldiston, G. W.; Jonas, A. M.

Laboratory Animal Science. Vol. 26 6. ed. 1976.

Research output: Chapter in Book/Report/Conference proceedingChapter

Barthold, SW, Coleman, GL, Bhatt, PN, Osbaldiston, GW & Jonas, AM 1976, The etiology of transmissible murine colonic hyperplasia. in Laboratory Animal Science. 6 edn, vol. 26.
Barthold SW, Coleman GL, Bhatt PN, Osbaldiston GW, Jonas AM. The etiology of transmissible murine colonic hyperplasia. In Laboratory Animal Science. 6 ed. Vol. 26. 1976
Barthold, Stephen W ; Coleman, G. L. ; Bhatt, P. N. ; Osbaldiston, G. W. ; Jonas, A. M. / The etiology of transmissible murine colonic hyperplasia. Laboratory Animal Science. Vol. 26 6. ed. 1976.
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