PURPOSE OF REVIEW: Percutaneous biopsy has an emerging role in the diagnosis and management of small renal masses. The increasing importance of percutaneous biopsy is related to both a better understanding of the natural history of these tumors as well as new developments in treatment strategies. RECENT FINDINGS: We discuss the emerging role of biopsy in the current practice setting. Additionally, we review recent data regarding its diagnostic accuracy, important technical considerations, and possible complications. Finally, we speculate on its future role in managing these patients. SUMMARY: The role of percutaneous renal biopsy in the management of small renal masses continues to evolve. It is critically important at this juncture to evaluate the benefits and shortcomings of such an approach.
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