The effects of ingested mammalian blood factors on vector arthropod immunity and physiology

Nazzy Pakpour, Leyla Akman-Anderson, Yoram Vodovotz, Shirley Luckhart

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

The blood feeding behavior of disease-transmitting arthropods creates a unique intersection between vertebrate and invertebrate physiology. Here, we review host blood-derived factors that persist through blood digestion to affect the lifespan, reproduction, and immune responses of some of the most common arthropod vectors of human disease.

Original languageEnglish (US)
Pages (from-to)243-254
Number of pages12
JournalMicrobes and Infection
Volume15
Issue number3
DOIs
StatePublished - Mar 2013

Keywords

  • Insulin
  • Macrophage migration inhibitory factor (MIF)
  • Mosquito
  • Plasmodium
  • Tick
  • Transforming growth factor-beta (TGF-β)

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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