Abstract
The present experiment examined the effects of ventromedial hypothalamic (VMH) lesions upon adipocyte number of adult female rats. Female Sprague-Dawley rats lesioned at 10 weeks of age and killed at 50 weeks displayed a two-fold increase in body weight and a four-fold cell number increase in the parametrial, retroperitoneal and subcutaneous adipose depots. Though at variance with several earlier reports on VMH-lesioned rats, these results add to a growing body of evidence that factors leading to overnutrition and excessive weight gain can produce significant increases in fat cell number even in the adult.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 295-301 |
| Number of pages | 7 |
| Journal | Nutrition Reports International |
| Volume | 23 |
| Issue number | 2 |
| State | Published - 1981 |
ASJC Scopus subject areas
- Food Science
- Biochemistry
- Endocrinology
- Medicine (miscellaneous)