TY - JOUR
T1 - The effect of spontaneous versus controlled ventilation on the rate of rise of alveolar halothane concentration in dogs
AU - Gibbons, R. T.
AU - Steffey, Eugene
AU - Eger, E. I.
PY - 1977/1/1
Y1 - 1977/1/1
N2 - The rate of rise of the alveolar : inspired halothane concentration (F(A)/F(I)) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4%. Initially, F(A)/F(I) rose at similar rates for all 3 concentrations, but at 4%, the plateau attained was lower as a result of respiratory depression. In a 2nd group of dogs, F(A)/F(I) was measured for inspired concentrations of 0.3, 1.5, 4, and 6% during controlled ventilation. F(A)/F(I) rose at similar rates at the lower 2 concentrations but at progressively more rapid rates at inspired concentrations of 4 and 6%, presumably as a result of circulatory depression.
AB - The rate of rise of the alveolar : inspired halothane concentration (F(A)/F(I)) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4%. Initially, F(A)/F(I) rose at similar rates for all 3 concentrations, but at 4%, the plateau attained was lower as a result of respiratory depression. In a 2nd group of dogs, F(A)/F(I) was measured for inspired concentrations of 0.3, 1.5, 4, and 6% during controlled ventilation. F(A)/F(I) rose at similar rates at the lower 2 concentrations but at progressively more rapid rates at inspired concentrations of 4 and 6%, presumably as a result of circulatory depression.
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M3 - Article
C2 - 556907
AN - SCOPUS:0017360199
VL - 56
SP - 32
EP - 34
JO - Anesthesia and Analgesia
JF - Anesthesia and Analgesia
SN - 0003-2999
IS - 1
ER -