Abstract
The rate of rise of the alveolar : inspired halothane concentration (F(A)/F(I)) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4%. Initially, F(A)/F(I) rose at similar rates for all 3 concentrations, but at 4%, the plateau attained was lower as a result of respiratory depression. In a 2nd group of dogs, F(A)/F(I) was measured for inspired concentrations of 0.3, 1.5, 4, and 6% during controlled ventilation. F(A)/F(I) rose at similar rates at the lower 2 concentrations but at progressively more rapid rates at inspired concentrations of 4 and 6%, presumably as a result of circulatory depression.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 32-34 |
| Number of pages | 3 |
| Journal | Anesthesia and Analgesia |
| Volume | 56 |
| Issue number | 1 |
| State | Published - Jan 1 1977 |
| Externally published | Yes |
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
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Gibbons, R. T., Steffey, E., & Eger, E. I. (1977). The effect of spontaneous versus controlled ventilation on the rate of rise of alveolar halothane concentration in dogs. Anesthesia and Analgesia, 56(1), 32-34.