The effect of individual components of soy formula and cows' milk formula on zinc bioavailability

B. Lonnerdal, A. Cederblad, L. Davidsson, B. Sandstrom

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Zinc absorption from human milk, cows' milk formulas, and soy formulas was studied in human adults by a radioisotope technique using 65Zn and whole body counting. Individual dietary components were investigated for effects on zinc absorption. Phytate was found to have a strong inhibitory effect on zinc absorption; addition of phytate to cows' milk formula (yielding a phytate concentration similar to that of soy formula) resulted in a decrease in zinc absorption from 31 to 16% similar to the absorption for soy formula (14%). Carbohydrate source, calcium, and zinc levels of the diet did not affect zinc absorption significantly. Iron supplementation of cows' milk formula decreased zinc absorption from 24 to 18% although this decrease was not found to be significant (p < 0.1). Absorption of zinc from a whey-adjusted cows' milk formula was higher (31%) than from a nonmodified cows' milk formula (22%). Increasing the zinc supplementation level in cows' milk formula but not in soy formula increased zinc absorption to approximate that from breast milk. It is suggested that reduction of phytate content of soy formula may be a more effective avenue of modification than increased level of zinc supplementation.

Original languageEnglish (US)
Pages (from-to)1064-1070
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume40
Issue number5
StatePublished - 1984

Fingerprint

Biological Availability
bioavailability
Zinc
Milk
zinc
milk
Phytic Acid
phytic acid
Human Milk
breast milk
Soy Milk
Whole-Body Counting
radionuclides
whey
Radioisotopes
dairy cows
Iron
Carbohydrates
iron
Diet

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Lonnerdal, B., Cederblad, A., Davidsson, L., & Sandstrom, B. (1984). The effect of individual components of soy formula and cows' milk formula on zinc bioavailability. American Journal of Clinical Nutrition, 40(5), 1064-1070.

The effect of individual components of soy formula and cows' milk formula on zinc bioavailability. / Lonnerdal, B.; Cederblad, A.; Davidsson, L.; Sandstrom, B.

In: American Journal of Clinical Nutrition, Vol. 40, No. 5, 1984, p. 1064-1070.

Research output: Contribution to journalArticle

Lonnerdal, B, Cederblad, A, Davidsson, L & Sandstrom, B 1984, 'The effect of individual components of soy formula and cows' milk formula on zinc bioavailability', American Journal of Clinical Nutrition, vol. 40, no. 5, pp. 1064-1070.
Lonnerdal, B. ; Cederblad, A. ; Davidsson, L. ; Sandstrom, B. / The effect of individual components of soy formula and cows' milk formula on zinc bioavailability. In: American Journal of Clinical Nutrition. 1984 ; Vol. 40, No. 5. pp. 1064-1070.
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