### Abstract

Zinc absorption from human milk, cows' milk formulas, and soy formulas was studied in human adults by a radioisotope technique using ^{65}Zn and whole body counting. Individual dietary components were investigated for effects on zinc absorption. Phytate was found to have a strong inhibitory effect on zinc absorption; addition of phytate to cows' milk formula (yielding a phytate concentration similar to that of soy formula) resulted in a decrease in zinc absorption from 31 to 16% similar to the absorption for soy formula (14%). Carbohydrate source, calcium, and zinc levels of the diet did not affect zinc absorption significantly. Iron supplementation of cows' milk formula decreased zinc absorption from 24 to 18% although this decrease was not found to be significant (p < 0.1). Absorption of zinc from a whey-adjusted cows' milk formula was higher (31%) than from a nonmodified cows' milk formula (22%). Increasing the zinc supplementation level in cows' milk formula but not in soy formula increased zinc absorption to approximate that from breast milk. It is suggested that reduction of phytate content of soy formula may be a more effective avenue of modification than increased level of zinc supplementation.

Original language | English (US) |
---|---|

Pages (from-to) | 1064-1070 |

Number of pages | 7 |

Journal | American Journal of Clinical Nutrition |

Volume | 40 |

Issue number | 5 |

State | Published - 1984 |

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### ASJC Scopus subject areas

- Food Science
- Medicine (miscellaneous)

### Cite this

*American Journal of Clinical Nutrition*,

*40*(5), 1064-1070.

**The effect of individual components of soy formula and cows' milk formula on zinc bioavailability.** / Lonnerdal, B.; Cederblad, A.; Davidsson, L.; Sandstrom, B.

Research output: Contribution to journal › Article

*American Journal of Clinical Nutrition*, vol. 40, no. 5, pp. 1064-1070.

}

TY - JOUR

T1 - The effect of individual components of soy formula and cows' milk formula on zinc bioavailability

AU - Lonnerdal, B.

AU - Cederblad, A.

AU - Davidsson, L.

AU - Sandstrom, B.

PY - 1984

Y1 - 1984

N2 - Zinc absorption from human milk, cows' milk formulas, and soy formulas was studied in human adults by a radioisotope technique using 65Zn and whole body counting. Individual dietary components were investigated for effects on zinc absorption. Phytate was found to have a strong inhibitory effect on zinc absorption; addition of phytate to cows' milk formula (yielding a phytate concentration similar to that of soy formula) resulted in a decrease in zinc absorption from 31 to 16% similar to the absorption for soy formula (14%). Carbohydrate source, calcium, and zinc levels of the diet did not affect zinc absorption significantly. Iron supplementation of cows' milk formula decreased zinc absorption from 24 to 18% although this decrease was not found to be significant (p < 0.1). Absorption of zinc from a whey-adjusted cows' milk formula was higher (31%) than from a nonmodified cows' milk formula (22%). Increasing the zinc supplementation level in cows' milk formula but not in soy formula increased zinc absorption to approximate that from breast milk. It is suggested that reduction of phytate content of soy formula may be a more effective avenue of modification than increased level of zinc supplementation.

AB - Zinc absorption from human milk, cows' milk formulas, and soy formulas was studied in human adults by a radioisotope technique using 65Zn and whole body counting. Individual dietary components were investigated for effects on zinc absorption. Phytate was found to have a strong inhibitory effect on zinc absorption; addition of phytate to cows' milk formula (yielding a phytate concentration similar to that of soy formula) resulted in a decrease in zinc absorption from 31 to 16% similar to the absorption for soy formula (14%). Carbohydrate source, calcium, and zinc levels of the diet did not affect zinc absorption significantly. Iron supplementation of cows' milk formula decreased zinc absorption from 24 to 18% although this decrease was not found to be significant (p < 0.1). Absorption of zinc from a whey-adjusted cows' milk formula was higher (31%) than from a nonmodified cows' milk formula (22%). Increasing the zinc supplementation level in cows' milk formula but not in soy formula increased zinc absorption to approximate that from breast milk. It is suggested that reduction of phytate content of soy formula may be a more effective avenue of modification than increased level of zinc supplementation.

UR - http://www.scopus.com/inward/record.url?scp=0021712974&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021712974&partnerID=8YFLogxK

M3 - Article

C2 - 6541868

AN - SCOPUS:0021712974

VL - 40

SP - 1064

EP - 1070

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 5

ER -