The effect of clinical chorioamnionitis on cord blood gas at term

Arnon Samueloff, Oded Langer, Michael D. Berkus, Nancy T Field, Elly M J Xenakis, Jeanna M. Piper

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective. We sought to determine the effect of clinical chorioamnionitis on cord blood gas values in term pregnancies not complicated by any other disease. Study design. 2200 consecutive deliveries were studied. Following exclusion of twins, non-viable malformations and stillbirths, as well as mothers with high-risk pregnancy diseases - i.e. hypertension, diabetes, preterm labor, third-trimester bleeding, IUGR, postdates, oligohydramnios, IV drug abused, decreased fetal movement, maternal viral infection, UTI or pneumonia (n = 897) - two groups of patients remained: term pregnancies complicated only by clinical chorioamnionitis (n = 81) and uncomplicated term pregnancies (n = 1246). Results. Evaluation of mean cord blood gas values revealed a significant difference in pH, Po2, Pco2 and BE values, with the infants of mothers with clinical chorioamnionitis having lower pH values (7.23 ± 0.07 vs. 7.28 ± 0.07). However, evaluating the independent effect of chorioamnionitis on arterial cord blood pH (using a logistic regression model) showed that clinical chorioamnionitis, by itself, did not contribute to this change in arterial cord blood pH. Conclusion. Chorioamnionitis was neither the explanation nor the cause for differences in arterial cord blood pH found between the two groups in our study. In cases of chorioamnionitis, these differences were attributed to other factors, such as length of labor, mode of delivery, method of delivery and presence of meconium.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume54
Issue number2
DOIs
StatePublished - 1994
Externally publishedYes

Fingerprint

Chorioamnionitis
blood gases
Fetal Blood
blood pH
Gases
pregnancy
labor
viral pneumonia
Mothers
fetal death
Pregnancy
hypertension
hemorrhage
diabetes
Logistic Models
Viral Pneumonia
Oligohydramnios
experimental design
High-Risk Pregnancy
Fetal Movement

Keywords

  • Arterial cord blood gas
  • Clinical chorioamnionitis
  • Logistic regression
  • pH

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine
  • Agricultural and Biological Sciences(all)

Cite this

The effect of clinical chorioamnionitis on cord blood gas at term. / Samueloff, Arnon; Langer, Oded; Berkus, Michael D.; Field, Nancy T; Xenakis, Elly M J; Piper, Jeanna M.

In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 54, No. 2, 1994, p. 87-91.

Research output: Contribution to journalArticle

Samueloff, Arnon ; Langer, Oded ; Berkus, Michael D. ; Field, Nancy T ; Xenakis, Elly M J ; Piper, Jeanna M. / The effect of clinical chorioamnionitis on cord blood gas at term. In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 1994 ; Vol. 54, No. 2. pp. 87-91.
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