TY - JOUR
T1 - The Effect of Acute Alcohol Intoxication and Chronic Alcohol Abuse on Outcome From Trauma
AU - Jurkovich, Gregory
AU - Rivara, Frederick P.
AU - Gurney, James G.
AU - Fligner, Corinne
AU - Ries, Richard
AU - Mueller, Beth A.
AU - Copass, Michael
PY - 1993/7/7
Y1 - 1993/7/7
N2 - To determine the effect of acute alcohol intoxication and chronic alcohol abuse on morbidity and mortality from trauma. —Prospective cohort study. —Blunt or penetrating trauma patients at least 18 years of age admitted to one trauma center or dying at the injury scene. —Mortality, complications (infection, pneumonia, respiratory failure, or multiple organ failure), and length of hospital stay. —Acute intoxication had no effect on risk of dying—at the injury scene, within the first 24 hours of hospitalization, after the first 24 hours, or overall. Acute intoxication also did not increase the risk of complications and was associated with shorter lengths of stay. Patients with both biochemical and behavioral evidence of chronic alcohol abuse had a twofold increased risk of complications, particularly pneumonia and any infection, compared with those with no evidence of chronic alcohol abuse. —Chronic, but not acute, alcohol abuse adversely affects outcome from trauma. Attention to the problem of chronic alcohol abuse in trauma patients is necessary, and screening trauma patients for chronic alcohol abuse appears to be warranted. (JAMA. 1993;270:51-56).
AB - To determine the effect of acute alcohol intoxication and chronic alcohol abuse on morbidity and mortality from trauma. —Prospective cohort study. —Blunt or penetrating trauma patients at least 18 years of age admitted to one trauma center or dying at the injury scene. —Mortality, complications (infection, pneumonia, respiratory failure, or multiple organ failure), and length of hospital stay. —Acute intoxication had no effect on risk of dying—at the injury scene, within the first 24 hours of hospitalization, after the first 24 hours, or overall. Acute intoxication also did not increase the risk of complications and was associated with shorter lengths of stay. Patients with both biochemical and behavioral evidence of chronic alcohol abuse had a twofold increased risk of complications, particularly pneumonia and any infection, compared with those with no evidence of chronic alcohol abuse. —Chronic, but not acute, alcohol abuse adversely affects outcome from trauma. Attention to the problem of chronic alcohol abuse in trauma patients is necessary, and screening trauma patients for chronic alcohol abuse appears to be warranted. (JAMA. 1993;270:51-56).
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U2 - 10.1001/jama.1993.03510010057029
DO - 10.1001/jama.1993.03510010057029
M3 - Article
C2 - 8510296
AN - SCOPUS:0027163024
VL - 270
SP - 51
EP - 56
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
SN - 0002-9955
IS - 1
ER -