The effect of a marathon run on plasma and urine mineral and metal concentrations

Alan L. Buchman, Carl Keen, Carl L Keen, Donna Killip, Ching Nan Ou, Cheryl L. Rognerud, Kenneth Dennis, J. Kay Dunn

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Background: Little data exist on the requirements of trace metals and minerals for endurance athletes. Changes in body status of these elements must be examined before specific nutritional recommendations can be made. This study was designed to determine whether a marathon run was associated with changes in serum and urine metal and mineral concentrations. Methods: Forty subjects who planned to complete the 1996 Houston-Tennaco marathon were recruited. Subjects had blood and urine samples collected 2 weeks prior to the race and immediately following the race. Blood and urine specimens were analyzed for copper, iron, magnesium and zinc concentrations. Blood was also analyzed for calcium concentration and ceruloplasmin activity. Results: Twenty-six subjects (24 male, 2 female) completed the marathon. Finish times varied between 2 hours 43 minutes and 5 hours 28 minutes. There was no significant change in serum calcium, copper or zinc concentrations or ceruloplasmin activity. Serum and urine magnesium concentration decreased significantly (19.55±1.73 to 16.55±1.53 ppm, p=0.00001; 34.02±8.64 to 21.80±12.24 ppm, p=0.003, respectively). Serum iron concentration increased significantly (1.060.48 to 1.35±0.42 ppm, p=0.006), while urine copper and iron concentrations were below the limits of detection, zinc concentration did not change. Conclusions: Serum and urinary magnesium concentrations decrease during endurance running, consistant with the possibility of magnesium deficiency. This may be related to increased demand in skeletal muscle. Serum iron concentration increases, possibly related to tissue injury. The exact etiology for these observations, as well as their clinical significance, requires further investigation.

Original languageEnglish (US)
Pages (from-to)124-127
Number of pages4
JournalJournal of the American College of Nutrition
Volume17
Issue number2
StatePublished - Apr 1998

Fingerprint

blood serum
Minerals
urine
Metals
metals
Urine
minerals
magnesium
Iron
Serum
iron
Magnesium
Zinc
Copper
ferroxidase
Ceruloplasmin
copper
zinc
trace elements
blood

Keywords

  • Calcium
  • Ceruloplasmin
  • Copper
  • Exercise
  • Iron
  • Magnesium
  • Zinc

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Buchman, A. L., Keen, C., Keen, C. L., Killip, D., Ou, C. N., Rognerud, C. L., ... Dunn, J. K. (1998). The effect of a marathon run on plasma and urine mineral and metal concentrations. Journal of the American College of Nutrition, 17(2), 124-127.

The effect of a marathon run on plasma and urine mineral and metal concentrations. / Buchman, Alan L.; Keen, Carl; Keen, Carl L; Killip, Donna; Ou, Ching Nan; Rognerud, Cheryl L.; Dennis, Kenneth; Dunn, J. Kay.

In: Journal of the American College of Nutrition, Vol. 17, No. 2, 04.1998, p. 124-127.

Research output: Contribution to journalArticle

Buchman, AL, Keen, C, Keen, CL, Killip, D, Ou, CN, Rognerud, CL, Dennis, K & Dunn, JK 1998, 'The effect of a marathon run on plasma and urine mineral and metal concentrations', Journal of the American College of Nutrition, vol. 17, no. 2, pp. 124-127.
Buchman AL, Keen C, Keen CL, Killip D, Ou CN, Rognerud CL et al. The effect of a marathon run on plasma and urine mineral and metal concentrations. Journal of the American College of Nutrition. 1998 Apr;17(2):124-127.
Buchman, Alan L. ; Keen, Carl ; Keen, Carl L ; Killip, Donna ; Ou, Ching Nan ; Rognerud, Cheryl L. ; Dennis, Kenneth ; Dunn, J. Kay. / The effect of a marathon run on plasma and urine mineral and metal concentrations. In: Journal of the American College of Nutrition. 1998 ; Vol. 17, No. 2. pp. 124-127.
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