The effect and stability of MVCT images on adaptive TomoTherapy

Poonam Yadav, Ranjini Tolakanahalli, Yi Rong, Bhudatt R. Paliwal

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Use of helical TomoTherapy-based MVCT imaging for adaptive planning is becomingincreasingly popular. Treatment planning and dose calculations based on MVCT require an image value to electron density calibration to remain stable over the course of treatment time. In this work, we have studied the dosimetric impact on TomoTherapy treatment plans due to variation in image value to density table (IVDT) curve as a function of target degradation. We also have investigated the reproducibility and stability of the TomoTherapy MVCT image quality over time. Multiple scans of the TomoTherapy "Cheese" phantom were performed over a periodof five months. Over this period, a difference of 4.7% in the HU values was observed inhigh-density regions while there was no significant variation in the image values for the low densities of the IVDT curve. Changes in the IVDT curves before and after target replacement were measured. Two clinical treatment sites, pelvis and prostate, were selected to study the dosimetric impact of this variation. Dose was recalculated on the MVCTs with the planned fluence using IVDT curves acquired before and after target change. For the cases studied, target replacement resulted in an overall difference of less than 5%, which can be significant for hypo-fractionated cases. Hence, it is recommended to measure the IVDT curves on a monthly basis and after any major repairs/replacements.

Original languageEnglish (US)
Pages (from-to)4-14
Number of pages11
JournalJournal of Applied Clinical Medical Physics
Issue number4
StatePublished - Jan 1 2010
Externally publishedYes


  • IVDT
  • MVCT
  • Target degradation
  • TomoTherapy

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging


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