The dynamic life of natural killer cells

Wayne M. Yokoyama, Sung Jin Kim, Anthony R. French

Research output: Contribution to journalReview articlepeer-review

430 Scopus citations


Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

Original languageEnglish (US)
Pages (from-to)405-429
Number of pages25
JournalAnnual Review of Immunology
StatePublished - 2004
Externally publishedYes


  • Development
  • Innate immunity
  • NK cells
  • Proliferation
  • Virus

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Medicine(all)


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