The diagnosis of oestrogen escape and the role of secondary orchiectomy in prostatic cancer

Anthony R Stone, T. B. Hargreave, G. D. Chisholm

Research output: Contribution to journalArticle

18 Scopus citations


The criteria for the diagnosis of progression of prostatic cancer after primary treatment by androgen suppression (oestrogen escape) were studied in 30 patients. Objective criteria are essential for this diagnosis and in this study the bone scan was the most useful criterion. Twenty one of these patients had a secondary orchiectomy: one patient showed a partial objective response and 3 had a subjective response. It is concluded that an orchiectomy following failed primary oestrogen therapy is an ineffective procedure and therefore unjustifiable and that alternative treatments must continue to be evaluated.

Original languageEnglish (US)
Pages (from-to)535-538
Number of pages4
JournalBritish Journal of Urology
Issue number6
StatePublished - 1980
Externally publishedYes


ASJC Scopus subject areas

  • Urology

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