The degradation of urate in liver peroxisomes

Association of allantoinase with allantoicase in amphibian liver but not in fish and invertebrate liver

Yoshikazu Takada, T. Noguchi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Allantoinase and allantoicase were co-purified from frog (Rana catesbeiana) liver. The ratio of the two enzyme activities remained constant during purification and was unchanged by a variety of treatments of the purified enzyme. These results suggest that allantoinase and allantoicase are located in the same protein. It was found that the two hepatic enzyme activities are also associated with the same protein in other frogs (Xenopus laevis and Rana nigromacultata), tadpoles (R. catesbeiana), and newts (Triturus pyrrhogaster). In contrast, allantoinase and allantoicase were found to be different proteins in marine fish and invertebrate liver.

Original languageEnglish (US)
Pages (from-to)4762-4764
Number of pages3
JournalJournal of Biological Chemistry
Volume258
Issue number8
StatePublished - 1983
Externally publishedYes

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allantoicase
Peroxisomes
Amphibians
Invertebrates
Uric Acid
Liver
Fish
Rana catesbeiana
Fishes
Enzyme activity
Degradation
Anura
Enzymes
Triturus
Ranidae
Salamandridae
Proteins
Xenopus laevis
Purification
Larva

ASJC Scopus subject areas

  • Biochemistry

Cite this

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abstract = "Allantoinase and allantoicase were co-purified from frog (Rana catesbeiana) liver. The ratio of the two enzyme activities remained constant during purification and was unchanged by a variety of treatments of the purified enzyme. These results suggest that allantoinase and allantoicase are located in the same protein. It was found that the two hepatic enzyme activities are also associated with the same protein in other frogs (Xenopus laevis and Rana nigromacultata), tadpoles (R. catesbeiana), and newts (Triturus pyrrhogaster). In contrast, allantoinase and allantoicase were found to be different proteins in marine fish and invertebrate liver.",
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T1 - The degradation of urate in liver peroxisomes

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AU - Noguchi, T.

PY - 1983

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