The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21

M. M. Locke; L. S. Ruth; L. V. Millon; Cecilia Penedo; J. D. Murray; A. T. Bowling

doi:10.1046/j.1365-2052.2001.00806.x

The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21

M. M. Locke, L. S. Ruth, L. V. Millon, Cecilia Penedo, J. D. Murray, A. T. Bowling

School of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of C^cr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to C^cr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)-C^cr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR).

Original language	English (US)
Pages (from-to)	340-343
Number of pages	4
Journal	Animal Genetics
Volume	32
Issue number	6
DOIs	https://doi.org/10.1046/j.1365-2052.2001.00806.x
State	Published - Dec 1 2001

Keywords

Buckskin
Coat colour
Cream
Dilution
Horse genetics
Microsatellite
Palomino

ASJC Scopus subject areas

Animal Science and Zoology
Genetics

Access to Document

10.1046/j.1365-2052.2001.00806.x

Fingerprint Dive into the research topics of 'The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21'. Together they form a unique fingerprint.

Cite this

@article{56e084b68f8947b0a8e302f53234f8db,

title = "The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21",

abstract = "The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of Ccr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to Ccr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)-Ccr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR).",

keywords = "Buckskin, Coat colour, Cream, Dilution, Horse genetics, Microsatellite, Palomino",

author = "Locke, {M. M.} and Ruth, {L. S.} and Millon, {L. V.} and Cecilia Penedo and Murray, {J. D.} and Bowling, {A. T.}",

year = "2001",

month = dec,

day = "1",

doi = "10.1046/j.1365-2052.2001.00806.x",

language = "English (US)",

volume = "32",

pages = "340--343",

journal = "Animal Genetics",

issn = "0268-9146",

publisher = "Wiley-Blackwell",

number = "6",

}

TY - JOUR

T1 - The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21

AU - Locke, M. M.

AU - Ruth, L. S.

AU - Millon, L. V.

AU - Penedo, Cecilia

AU - Murray, J. D.

AU - Bowling, A. T.

PY - 2001/12/1

Y1 - 2001/12/1

N2 - The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of Ccr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to Ccr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)-Ccr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR).

AB - The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of Ccr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to Ccr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)-Ccr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR).

KW - Buckskin

KW - Coat colour

KW - Cream

KW - Dilution

KW - Horse genetics

KW - Microsatellite

KW - Palomino

UR - http://www.scopus.com/inward/record.url?scp=0035543325&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035543325&partnerID=8YFLogxK

U2 - 10.1046/j.1365-2052.2001.00806.x

DO - 10.1046/j.1365-2052.2001.00806.x

M3 - Article

C2 - 11736803

AN - SCOPUS:0035543325

VL - 32

SP - 340

EP - 343

JO - Animal Genetics

JF - Animal Genetics

SN - 0268-9146

IS - 6

ER -