The core-inversible micelles for hydrophilic drug delivery

Wenzhe Huang, Changying Shi, Yu Shao, Kit Lam, Juntao Luo

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A unique core-inversible micelle (CIM) was formed via PEG 5kCA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

Original languageEnglish (US)
Pages (from-to)6674-6676
Number of pages3
JournalChemical Communications
Volume49
Issue number59
DOIs
StatePublished - Jul 28 2013

Fingerprint

Congo Red
Micelles
Drug delivery
Folic Acid
Polyethylene glycols
Cells
Molecules
Amyloid
Water

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

The core-inversible micelles for hydrophilic drug delivery. / Huang, Wenzhe; Shi, Changying; Shao, Yu; Lam, Kit; Luo, Juntao.

In: Chemical Communications, Vol. 49, No. 59, 28.07.2013, p. 6674-6676.

Research output: Contribution to journalArticle

Huang, Wenzhe ; Shi, Changying ; Shao, Yu ; Lam, Kit ; Luo, Juntao. / The core-inversible micelles for hydrophilic drug delivery. In: Chemical Communications. 2013 ; Vol. 49, No. 59. pp. 6674-6676.
@article{dc46377ed36743b18fbfadc2afbba867,
title = "The core-inversible micelles for hydrophilic drug delivery",
abstract = "A unique core-inversible micelle (CIM) was formed via PEG 5kCA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.",
author = "Wenzhe Huang and Changying Shi and Yu Shao and Kit Lam and Juntao Luo",
year = "2013",
month = "7",
day = "28",
doi = "10.1039/c3cc43209b",
language = "English (US)",
volume = "49",
pages = "6674--6676",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "59",

}

TY - JOUR

T1 - The core-inversible micelles for hydrophilic drug delivery

AU - Huang, Wenzhe

AU - Shi, Changying

AU - Shao, Yu

AU - Lam, Kit

AU - Luo, Juntao

PY - 2013/7/28

Y1 - 2013/7/28

N2 - A unique core-inversible micelle (CIM) was formed via PEG 5kCA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

AB - A unique core-inversible micelle (CIM) was formed via PEG 5kCA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

UR - http://www.scopus.com/inward/record.url?scp=84879776652&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879776652&partnerID=8YFLogxK

U2 - 10.1039/c3cc43209b

DO - 10.1039/c3cc43209b

M3 - Article

C2 - 23775217

AN - SCOPUS:84879776652

VL - 49

SP - 6674

EP - 6676

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 59

ER -