The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease

Thomas T. Tsai; Thomas F. Rehring; R. Kevin Rogers; Susan M. Shetterly; Nicole M. Wagner; Rajan Gupta; Omid Jazaeri; Nasim Hedayati; W. Schuyler Jones; Manesh R. Patel; P. Michael Ho; Alan S. Go; David J. Magid

doi:10.1161/CIRCULATIONAHA.114.013440

The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease

Thomas T. Tsai, Thomas F. Rehring, R. Kevin Rogers, Susan M. Shetterly, Nicole M. Wagner, Rajan Gupta, Omid Jazaeri, Nasim Hedayati, W. Schuyler Jones, Manesh R. Patel, P. Michael Ho, Alan S. Go, David J. Magid

Vascular Surgery

Research output: Contribution to journal › Article

29 Scopus citations

Abstract

Background - Treatment for symptomatic peripheral artery disease includes lower extremity bypass surgery (LEB) and peripheral endovascular interventions (PVIs); however, limited comparative effectiveness data exist between the 2 therapies. We assessed the safety and effectiveness of LEB and PVI in patients with symptomatic claudication and critical limb ischemia. Methods and Results - In a community-based clinical registry at 2 large integrated healthcare delivery systems, we compared 883 patients undergoing PVI and 975 patients undergoing LEB between January 1, 2005 and December 31, 2011. Rates of target lesion revascularization were greater for PVI than for LEB in patients presenting with claudication (12.3±2.7% and 19.0±3.5% at 1 and 3 years versus 5.2±2.4% and 8.3±3.1%, log-rank P

Original language	English (US)
Pages (from-to)	1999-2011
Number of pages	13
Journal	Circulation
Volume	132
Issue number	21
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.114.013440
State	Published - Nov 24 2015

Keywords

comparative effectiveness research
lower extremity bypass surgery
peripheral arterial disease

ASJC Scopus subject areas

Physiology (medical)
Cardiology and Cardiovascular Medicine

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Tsai, T. T., Rehring, T. F., Rogers, R. K., Shetterly, S. M., Wagner, N. M., Gupta, R., Jazaeri, O., Hedayati, N., Jones, W. S., Patel, M. R., Ho, P. M., Go, A. S., & Magid, D. J. (2015). The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease. Circulation, 132(21), 1999-2011. https://doi.org/10.1161/CIRCULATIONAHA.114.013440

The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease. / Tsai, Thomas T.; Rehring, Thomas F.; Rogers, R. Kevin; Shetterly, Susan M.; Wagner, Nicole M.; Gupta, Rajan; Jazaeri, Omid; Hedayati, Nasim; Jones, W. Schuyler; Patel, Manesh R.; Ho, P. Michael; Go, Alan S.; Magid, David J.

In: Circulation, Vol. 132, No. 21, 24.11.2015, p. 1999-2011.

Research output: Contribution to journal › Article

Tsai, TT, Rehring, TF, Rogers, RK, Shetterly, SM, Wagner, NM, Gupta, R, Jazaeri, O, Hedayati, N, Jones, WS, Patel, MR, Ho, PM, Go, AS & Magid, DJ 2015, 'The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease', Circulation, vol. 132, no. 21, pp. 1999-2011. https://doi.org/10.1161/CIRCULATIONAHA.114.013440

Tsai, Thomas T. ; Rehring, Thomas F. ; Rogers, R. Kevin ; Shetterly, Susan M. ; Wagner, Nicole M. ; Gupta, Rajan ; Jazaeri, Omid ; Hedayati, Nasim ; Jones, W. Schuyler ; Patel, Manesh R. ; Ho, P. Michael ; Go, Alan S. ; Magid, David J. / The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease. In: Circulation. 2015 ; Vol. 132, No. 21. pp. 1999-2011.

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abstract = "Background - Treatment for symptomatic peripheral artery disease includes lower extremity bypass surgery (LEB) and peripheral endovascular interventions (PVIs); however, limited comparative effectiveness data exist between the 2 therapies. We assessed the safety and effectiveness of LEB and PVI in patients with symptomatic claudication and critical limb ischemia. Methods and Results - In a community-based clinical registry at 2 large integrated healthcare delivery systems, we compared 883 patients undergoing PVI and 975 patients undergoing LEB between January 1, 2005 and December 31, 2011. Rates of target lesion revascularization were greater for PVI than for LEB in patients presenting with claudication (12.3±2.7% and 19.0±3.5% at 1 and 3 years versus 5.2±2.4% and 8.3±3.1%, log-rank P",

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