The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease

Thomas T. Tsai, Thomas F. Rehring, R. Kevin Rogers, Susan M. Shetterly, Nicole M. Wagner, Rajan Gupta, Omid Jazaeri, Nasim Hedayati, W. Schuyler Jones, Manesh R. Patel, P. Michael Ho, Alan S. Go, David J. Magid

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Background - Treatment for symptomatic peripheral artery disease includes lower extremity bypass surgery (LEB) and peripheral endovascular interventions (PVIs); however, limited comparative effectiveness data exist between the 2 therapies. We assessed the safety and effectiveness of LEB and PVI in patients with symptomatic claudication and critical limb ischemia. Methods and Results - In a community-based clinical registry at 2 large integrated healthcare delivery systems, we compared 883 patients undergoing PVI and 975 patients undergoing LEB between January 1, 2005 and December 31, 2011. Rates of target lesion revascularization were greater for PVI than for LEB in patients presenting with claudication (12.3±2.7% and 19.0±3.5% at 1 and 3 years versus 5.2±2.4% and 8.3±3.1%, log-rank P

Original languageEnglish (US)
Pages (from-to)1999-2011
Number of pages13
JournalCirculation
Volume132
Issue number21
DOIs
StatePublished - Nov 24 2015

Keywords

  • comparative effectiveness research
  • lower extremity bypass surgery
  • peripheral arterial disease

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

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    Tsai, T. T., Rehring, T. F., Rogers, R. K., Shetterly, S. M., Wagner, N. M., Gupta, R., Jazaeri, O., Hedayati, N., Jones, W. S., Patel, M. R., Ho, P. M., Go, A. S., & Magid, D. J. (2015). The contemporary safety and effectiveness of lower extremity bypass surgery and peripheral endovascular interventions in the treatment of symptomatic peripheral arterial disease. Circulation, 132(21), 1999-2011. https://doi.org/10.1161/CIRCULATIONAHA.114.013440