The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

Jonathan A Eisen, Karen E. Nelson, Ian T. Paulsen, John F. Heidelberg, Martin Wu, Robert J. Dodson, Robert Deboy, Michelle L. Gwinn, William C. Nelson, Daniel H. Haft, Erin K. Hickey, Jeremy D. Peterson, A. Scott Durkin, James L. Kolonay, Fan Yang, Ingeborg Holt, Lowell A. Umayam, Tanya Mason, Michael Brenner, Terrance P. Shea & 15 others Debbie Parksey, William C. Nierman, Tamara V. Feldblyum, Cheryl L. Hansen, M. Brook Craven, Diana Radune, Jessica Vamathevan, Hoda Khouri, Owen White, Tanja M. Gruber, Karen A. Ketchum, J. Craig Venter, Hervé Tettelin, Donald A. Bryant, Claire M. Fraser

Research output: Contribution to journalArticle

236 Citations (Scopus)

Abstract

The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C tepidum and many Archaeal species.

Original languageEnglish (US)
Pages (from-to)9509-9514
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume99
Issue number14
DOIs
StatePublished - Jul 9 2002
Externally publishedYes

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Chlorobium
Chlorobi
Photosynthesis
Genome
Sulfur
Photobiology
Eubacterium
Gene Duplication
Chromosomes, Human, Pair 2
Citric Acid Cycle
Biosynthetic Pathways
Nitrogen
Genes

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. / Eisen, Jonathan A; Nelson, Karen E.; Paulsen, Ian T.; Heidelberg, John F.; Wu, Martin; Dodson, Robert J.; Deboy, Robert; Gwinn, Michelle L.; Nelson, William C.; Haft, Daniel H.; Hickey, Erin K.; Peterson, Jeremy D.; Durkin, A. Scott; Kolonay, James L.; Yang, Fan; Holt, Ingeborg; Umayam, Lowell A.; Mason, Tanya; Brenner, Michael; Shea, Terrance P.; Parksey, Debbie; Nierman, William C.; Feldblyum, Tamara V.; Hansen, Cheryl L.; Craven, M. Brook; Radune, Diana; Vamathevan, Jessica; Khouri, Hoda; White, Owen; Gruber, Tanja M.; Ketchum, Karen A.; Venter, J. Craig; Tettelin, Hervé; Bryant, Donald A.; Fraser, Claire M.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 14, 09.07.2002, p. 9509-9514.

Research output: Contribution to journalArticle

Eisen, JA, Nelson, KE, Paulsen, IT, Heidelberg, JF, Wu, M, Dodson, RJ, Deboy, R, Gwinn, ML, Nelson, WC, Haft, DH, Hickey, EK, Peterson, JD, Durkin, AS, Kolonay, JL, Yang, F, Holt, I, Umayam, LA, Mason, T, Brenner, M, Shea, TP, Parksey, D, Nierman, WC, Feldblyum, TV, Hansen, CL, Craven, MB, Radune, D, Vamathevan, J, Khouri, H, White, O, Gruber, TM, Ketchum, KA, Venter, JC, Tettelin, H, Bryant, DA & Fraser, CM 2002, 'The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium', Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 14, pp. 9509-9514. https://doi.org/10.1073/pnas.132181499
Eisen, Jonathan A ; Nelson, Karen E. ; Paulsen, Ian T. ; Heidelberg, John F. ; Wu, Martin ; Dodson, Robert J. ; Deboy, Robert ; Gwinn, Michelle L. ; Nelson, William C. ; Haft, Daniel H. ; Hickey, Erin K. ; Peterson, Jeremy D. ; Durkin, A. Scott ; Kolonay, James L. ; Yang, Fan ; Holt, Ingeborg ; Umayam, Lowell A. ; Mason, Tanya ; Brenner, Michael ; Shea, Terrance P. ; Parksey, Debbie ; Nierman, William C. ; Feldblyum, Tamara V. ; Hansen, Cheryl L. ; Craven, M. Brook ; Radune, Diana ; Vamathevan, Jessica ; Khouri, Hoda ; White, Owen ; Gruber, Tanja M. ; Ketchum, Karen A. ; Venter, J. Craig ; Tettelin, Hervé ; Bryant, Donald A. ; Fraser, Claire M. / The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. In: Proceedings of the National Academy of Sciences of the United States of America. 2002 ; Vol. 99, No. 14. pp. 9509-9514.
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AU - Khouri, Hoda

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