The clinical spectrum of prostate cancer

Ralph W deVere White, D. F. Paulson, J. F. Glenn

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Review of 206 consecutive patients with prostatic carcinoma and a potential for 10 yr followup indicates the efficacy of vigorous surgical or hormonal management. Satisfactory documented followup was achieved in 88% of the group for 5 yr and 82% of the group for 10 yr. Among 33 patients undergoing radical perineal prostatectomy survival rates were 84% at 5 yr and 58% at 10 yr. In the entire series, irrespective of modality of treatment, approximately half of the patients survived 5 yr and a 4th for 10 yr. Hormonal therapy of choice was orchiectomy combined with relatively high doses of estrogens, with no indication of significant cardiovascular morbidity or mortality. Interestingly, stage A disease (often diffuse, anaplastic and unsuspected) demonstrated a significantly increased mortality risk when compared to stage B (localized and usually well differentiated) carcinoma of the prostate.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalJournal of Urology
Issue number3
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Urology


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