TY - JOUR
T1 - The clinical spectrum of prostate cancer
AU - deVere White, Ralph W
AU - Paulson, D. F.
AU - Glenn, J. F.
PY - 1977
Y1 - 1977
N2 - Review of 206 consecutive patients with prostatic carcinoma and a potential for 10 yr followup indicates the efficacy of vigorous surgical or hormonal management. Satisfactory documented followup was achieved in 88% of the group for 5 yr and 82% of the group for 10 yr. Among 33 patients undergoing radical perineal prostatectomy survival rates were 84% at 5 yr and 58% at 10 yr. In the entire series, irrespective of modality of treatment, approximately half of the patients survived 5 yr and a 4th for 10 yr. Hormonal therapy of choice was orchiectomy combined with relatively high doses of estrogens, with no indication of significant cardiovascular morbidity or mortality. Interestingly, stage A disease (often diffuse, anaplastic and unsuspected) demonstrated a significantly increased mortality risk when compared to stage B (localized and usually well differentiated) carcinoma of the prostate.
AB - Review of 206 consecutive patients with prostatic carcinoma and a potential for 10 yr followup indicates the efficacy of vigorous surgical or hormonal management. Satisfactory documented followup was achieved in 88% of the group for 5 yr and 82% of the group for 10 yr. Among 33 patients undergoing radical perineal prostatectomy survival rates were 84% at 5 yr and 58% at 10 yr. In the entire series, irrespective of modality of treatment, approximately half of the patients survived 5 yr and a 4th for 10 yr. Hormonal therapy of choice was orchiectomy combined with relatively high doses of estrogens, with no indication of significant cardiovascular morbidity or mortality. Interestingly, stage A disease (often diffuse, anaplastic and unsuspected) demonstrated a significantly increased mortality risk when compared to stage B (localized and usually well differentiated) carcinoma of the prostate.
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M3 - Article
C2 - 839594
AN - SCOPUS:0017347783
VL - 117
SP - 323
EP - 327
JO - Investigative Urology
JF - Investigative Urology
SN - 0022-5347
IS - 3
ER -