The changing roles of steroid nuclear receptors with prostate cancer progression

Rosalinda M. Savoy; Paramita M Ghosh

doi:10.1530/ERC-13-0193

The changing roles of steroid nuclear receptors with prostate cancer progression

Rosalinda M. Savoy, Paramita M Ghosh

Urology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Estrogens were once used for the treatment of prostate cancer (PC). They may still be used in various parts of the world to that effect. Recent developments in the understanding of a role for estrogen receptor b (ERb) in the development and progression of this disease resurrect the discussion on the intertwined roles of ER b and the androgen receptor (AR) in promoting PC. A new article by Zellweger et al. in Endocrine-Related Cancer investigates the expression and assesses the activity of ERa and ERb as well as the AR, in addition to a phosphorylated form of AR in hormone-naïve and castration-resistant PC.

Original language	English (US)
Journal	Endocrine-Related Cancer
Volume	20
Issue number	4
DOIs	https://doi.org/10.1530/ERC-13-0193
State	Published - Aug 2013

Keywords

Androgen receptor
Estrogen receptor β
Hormone-naïve
Prostate cancer
Serine 210 phosphorylation

ASJC Scopus subject areas

Endocrinology
Oncology
Cancer Research
Endocrinology, Diabetes and Metabolism

Access to Document

10.1530/ERC-13-0193

Cite this

@article{cf9d016017ef47feb500daeb8507c47c,

title = "The changing roles of steroid nuclear receptors with prostate cancer progression",

abstract = "Estrogens were once used for the treatment of prostate cancer (PC). They may still be used in various parts of the world to that effect. Recent developments in the understanding of a role for estrogen receptor b (ERb) in the development and progression of this disease resurrect the discussion on the intertwined roles of ER b and the androgen receptor (AR) in promoting PC. A new article by Zellweger et al. in Endocrine-Related Cancer investigates the expression and assesses the activity of ERa and ERb as well as the AR, in addition to a phosphorylated form of AR in hormone-na{\"i}ve and castration-resistant PC.",

keywords = "Androgen receptor, Estrogen receptor β, Hormone-na{\"i}ve, Prostate cancer, Serine 210 phosphorylation",

author = "Savoy, {Rosalinda M.} and Ghosh, {Paramita M}",

year = "2013",

month = aug,

doi = "10.1530/ERC-13-0193",

language = "English (US)",

volume = "20",

journal = "Endocrine-Related Cancer",

issn = "1351-0088",

publisher = "Society for Endocrinology",

number = "4",

}

TY - JOUR

T1 - The changing roles of steroid nuclear receptors with prostate cancer progression

AU - Savoy, Rosalinda M.

AU - Ghosh, Paramita M

PY - 2013/8

Y1 - 2013/8

N2 - Estrogens were once used for the treatment of prostate cancer (PC). They may still be used in various parts of the world to that effect. Recent developments in the understanding of a role for estrogen receptor b (ERb) in the development and progression of this disease resurrect the discussion on the intertwined roles of ER b and the androgen receptor (AR) in promoting PC. A new article by Zellweger et al. in Endocrine-Related Cancer investigates the expression and assesses the activity of ERa and ERb as well as the AR, in addition to a phosphorylated form of AR in hormone-naïve and castration-resistant PC.

AB - Estrogens were once used for the treatment of prostate cancer (PC). They may still be used in various parts of the world to that effect. Recent developments in the understanding of a role for estrogen receptor b (ERb) in the development and progression of this disease resurrect the discussion on the intertwined roles of ER b and the androgen receptor (AR) in promoting PC. A new article by Zellweger et al. in Endocrine-Related Cancer investigates the expression and assesses the activity of ERa and ERb as well as the AR, in addition to a phosphorylated form of AR in hormone-naïve and castration-resistant PC.

KW - Androgen receptor

KW - Estrogen receptor β

KW - Hormone-naïve

KW - Prostate cancer

KW - Serine 210 phosphorylation

UR - http://www.scopus.com/inward/record.url?scp=84882797893&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882797893&partnerID=8YFLogxK

U2 - 10.1530/ERC-13-0193

DO - 10.1530/ERC-13-0193

M3 - Article

C2 - 23744763

AN - SCOPUS:84882797893

VL - 20

JO - Endocrine-Related Cancer

JF - Endocrine-Related Cancer

SN - 1351-0088

IS - 4

ER -

The changing roles of steroid nuclear receptors with prostate cancer progression

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this