The association of radiographic changes of osteoarthritis of the hand and hip in elderly women

M. C. Hochberg, Nancy E Lane, A. R. Pressman, H. K. Genant, J. C. Scott, M. C. Nevitt

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Objective. To examine the association of radiographic features of hand and hip osteoarthritis (OA) in elderly women. Methods. Hand and hip radiographs were read for changes of OA from a sample of 1422 women aged 65 and above who were participants in the Study of Osteoporotic Fractures. Definite hip OA required the presence of 2 or more of the following: moderate or large osteophytes, moderate or severe joint space narrowing, subchondral sclerosis, cysts, and femoral head deformity. Definite hand OA required moderate or large osteophytes at 2 or more of the following 6 sites: 2nd and 3rd distal and proximal interphalangeal joints and 1st interphalangeal and carpometacarpal joints. Data were analyzed using multiple logistic regression adjusting for age, weight at age 50, and current height. Results. Overall, 147 (10.4%) women had radiographic changes of definite hip OA and 68 (4.8%) had severe hip OA; 56 had bilateral and 87 had unilateral disease. Definite hand OA was present in 732 (51.4%) women. Hand OA was significantly associated with definite hip OA [odds ratio (OR) = 3.25, 95% confidence intervals (CI) 2.19, 4.84], and severe hip OA (OR = 3.23, 95% CI 1.82, 5.73). Hand OA was significantly associated with bilateral hip OA (OR = 3.54, 95% CI 1.87, 6.73) as well as unilateral hip OA (OR = 3.06, 95% CI 1.84, 5.08). Conclusion. These data are consistent with the inclusion of radiographically defined hip OA in the construct of generalized OA, particularly in elderly women.

Original languageEnglish (US)
Pages (from-to)2291-2294
Number of pages4
JournalJournal of Rheumatology
Volume22
Issue number12
StatePublished - 1995
Externally publishedYes

Fingerprint

Hip Osteoarthritis
Hand
Osteoarthritis
Odds Ratio
Confidence Intervals
Osteophyte
Joints
Carpometacarpal Joints
Bone Cysts
Osteoporotic Fractures
Sclerosis
Hip
Logistic Models
Weights and Measures

Keywords

  • Epidemiology
  • Osteoarthritis

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Hochberg, M. C., Lane, N. E., Pressman, A. R., Genant, H. K., Scott, J. C., & Nevitt, M. C. (1995). The association of radiographic changes of osteoarthritis of the hand and hip in elderly women. Journal of Rheumatology, 22(12), 2291-2294.

The association of radiographic changes of osteoarthritis of the hand and hip in elderly women. / Hochberg, M. C.; Lane, Nancy E; Pressman, A. R.; Genant, H. K.; Scott, J. C.; Nevitt, M. C.

In: Journal of Rheumatology, Vol. 22, No. 12, 1995, p. 2291-2294.

Research output: Contribution to journalArticle

Hochberg, MC, Lane, NE, Pressman, AR, Genant, HK, Scott, JC & Nevitt, MC 1995, 'The association of radiographic changes of osteoarthritis of the hand and hip in elderly women', Journal of Rheumatology, vol. 22, no. 12, pp. 2291-2294.
Hochberg MC, Lane NE, Pressman AR, Genant HK, Scott JC, Nevitt MC. The association of radiographic changes of osteoarthritis of the hand and hip in elderly women. Journal of Rheumatology. 1995;22(12):2291-2294.
Hochberg, M. C. ; Lane, Nancy E ; Pressman, A. R. ; Genant, H. K. ; Scott, J. C. ; Nevitt, M. C. / The association of radiographic changes of osteoarthritis of the hand and hip in elderly women. In: Journal of Rheumatology. 1995 ; Vol. 22, No. 12. pp. 2291-2294.
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abstract = "Objective. To examine the association of radiographic features of hand and hip osteoarthritis (OA) in elderly women. Methods. Hand and hip radiographs were read for changes of OA from a sample of 1422 women aged 65 and above who were participants in the Study of Osteoporotic Fractures. Definite hip OA required the presence of 2 or more of the following: moderate or large osteophytes, moderate or severe joint space narrowing, subchondral sclerosis, cysts, and femoral head deformity. Definite hand OA required moderate or large osteophytes at 2 or more of the following 6 sites: 2nd and 3rd distal and proximal interphalangeal joints and 1st interphalangeal and carpometacarpal joints. Data were analyzed using multiple logistic regression adjusting for age, weight at age 50, and current height. Results. Overall, 147 (10.4{\%}) women had radiographic changes of definite hip OA and 68 (4.8{\%}) had severe hip OA; 56 had bilateral and 87 had unilateral disease. Definite hand OA was present in 732 (51.4{\%}) women. Hand OA was significantly associated with definite hip OA [odds ratio (OR) = 3.25, 95{\%} confidence intervals (CI) 2.19, 4.84], and severe hip OA (OR = 3.23, 95{\%} CI 1.82, 5.73). Hand OA was significantly associated with bilateral hip OA (OR = 3.54, 95{\%} CI 1.87, 6.73) as well as unilateral hip OA (OR = 3.06, 95{\%} CI 1.84, 5.08). Conclusion. These data are consistent with the inclusion of radiographically defined hip OA in the construct of generalized OA, particularly in elderly women.",
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