The association of inadequate mid-pregnancy weight gain and preterm birth in twin pregnancies

K. E. Pettit, D. Y. Lacoursiere, David B Schrimmer, H. Alblewi, T. R. Moore, G. A. Ramos

Research output: Contribution to journalArticle

13 Scopus citations


OBJECTIVE: To determine whether inadequate gestational weight gain in the second trimester in twin pregnancies is associated with an increased risk of preterm birth (PTB) at <32 weeks. STUDY DESIGN: Retrospective cohort study including 489 twin pregnancies delivered between 2001 and 2013. Rates of weight gain at different gestational ages were compared with Institute of Medicine guidelines. RESULT: An inadequate rate of weight gain at <20 weeks was not associated with PTB. Patients with inadequate rates of weight gain at 20 to 28 weeks had a higher risk of PTB at <32 weeks (37.6%) compared to those with adequate weight gain (15.2%) (P < 0.001). In multivariate analysis, women with inadequate weight gain at 20 to 28 weeks were 2.8 times more likely to deliver at <32 weeks (95% confidence interval 1.65 to 4.81). CONCLUSION: Inadequate gestational weight gain at 20 to 28 weeks in twin pregnancies was the strongest predictor of PTB at <32 weeks. This represents an optimal time for interventions to improve weight gain and potentially decrease rates of PTB.

Original languageEnglish (US)
Pages (from-to)85-89
Number of pages5
JournalJournal of Perinatology
Issue number2
StatePublished - Mar 2 2015
Externally publishedYes


ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)

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