The age of the Arabidopsis thaliana genome duplication

Maria D. Ermolaeva, Martin Wu, Jonathan A Eisen, Steven L. Salzberg

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

We estimate the timing of the Arabidopsis thaliana whole-genome duplication by means of phylogenetic and statistical analysis, and propose two possible scenarios for the duplication. The first one, based on the assumption that the duplicated segments diverged from an autotetraploid form, places the duplication at about 38 million years ago, after the Arabidopsis lineage diverged from that of soybean (Glycine max) and before it diverged from its sister genus, Brassica. The second scenario assumes that the ancestor was allotetraploid, and suggests that the duplication is younger than 38 million years and may have contributed to the Arabidopsis-Brassica divergence. In each case, our estimate places the age of the genome duplication as significantly younger than previously reported.

Original languageEnglish (US)
Pages (from-to)859-866
Number of pages8
JournalPlant Molecular Biology
Volume51
Issue number6
DOIs
StatePublished - Apr 2003
Externally publishedYes

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Brassica
Arabidopsis
Arabidopsis thaliana
Genes
Genome
Soybeans
genome
Glycine
Glycine max
Statistical methods
ancestry
statistical analysis
soybeans
phylogeny

Keywords

  • Arabidopsis
  • Bioinformatics
  • Evolution
  • Gene loss
  • Genome duplication

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

The age of the Arabidopsis thaliana genome duplication. / Ermolaeva, Maria D.; Wu, Martin; Eisen, Jonathan A; Salzberg, Steven L.

In: Plant Molecular Biology, Vol. 51, No. 6, 04.2003, p. 859-866.

Research output: Contribution to journalArticle

Ermolaeva, Maria D. ; Wu, Martin ; Eisen, Jonathan A ; Salzberg, Steven L. / The age of the Arabidopsis thaliana genome duplication. In: Plant Molecular Biology. 2003 ; Vol. 51, No. 6. pp. 859-866.
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