The adenovirus that causes hemorrhagic disease of black-tailed deer is closely related to bovine adenovirus-3

J. M. Lapointe, J. F. Hedges, Leslie Woods, G. H. Reubel, Nigel J Maclachlan

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10 Scopus citations


DNA sequence data was obtained from an adenovirus previously shown to be the cause of a distinctive, fatal hemorrhagic disease of black-tailed deer in California. A 256 base fragment of the viral hexon gene was amplified by PCR from purified adenovirus preparations. The amplicon then was cloned and sequenced. Phylogenetic relationships with other mammalian adenoviruses were also determined. Although sequence analysis of this portion of the hexon gene indicates that the black-tailed deer adenovirus is closely related to bovine adenovirus-3, the biologic properties of the two viruses are clearly distinct.

Original languageEnglish (US)
Pages (from-to)393-396
Number of pages4
JournalArchives of Virology
Issue number2
StatePublished - 1999


ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

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