The acquisition of a kindled response in developing rats using 24-h intertrial intervals

Larry G. Stark, Timothy E Albertson, Robert M. Joy, Pingnian He, Janice Streisand

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The purpose of this study was to evaluate a methodology which would permit serial EEG recordings and daily amygdaloid kindling stimulations in young rats (16-26 days old). The preparation was sufficient to maintain the developing rats for 26 consecutive days of stimulation and recording and to permit the acquisition of kindled seizures. Developing rats required a slightly greater number of trials to acquire the kindled response than did adult rats in previous studies using a 24-h intertrial interval.

Original languageEnglish (US)
Pages (from-to)291-294
Number of pages4
JournalDevelopmental Brain Research
Volume24
Issue number1-2
DOIs
StatePublished - 1986

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Keywords

  • amygdala
  • development
  • infant
  • kindling
  • rat
  • seizure
  • weanling

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

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