Abstract
Cerebral blood flow was analyzed by the stable xenon (Xe)/CT scanning technique in 29 patients with significant vascular lesions before and after administration of an acetazolamide (Diamox) vasodilatory challenge. Three response types were identified: I, normal flow before Diamox with flow augmentation after Diamox; II, low flow before Diamox with flow augmentation after Diamox; and III, low or normal flow before Diamox with no augmentation or decreased flow after Diamox. Twenty-four percent of the patients studied qualified for category III. We believe that patients in this category represent a group of individuals without blood flow reserve whose clinical management should include careful consideration of their hemodynamic status. The Xe/CT scanning technique with the addition of Diamox flow challenge is a clinically accessible and effective method for assessing cerebral blood flow and blood flow reserve.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 803-810 |
| Number of pages | 8 |
| Journal | American Journal of Neuroradiology |
| Volume | 10 |
| Issue number | 4 |
| State | Published - 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Clinical Neurology
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
The acetazolamide challenge : imaging techniques designed to evaluate cerebral blood flow reserve. / Rogg, J.; Rutigliano, M.; Yonas, H.; Johnson, D. W.; Pentheny, S.; Latchaw, Richard E.
In: American Journal of Neuroradiology, Vol. 10, No. 4, 1989, p. 803-810.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The acetazolamide challenge
T2 - imaging techniques designed to evaluate cerebral blood flow reserve
AU - Rogg, J.
AU - Rutigliano, M.
AU - Yonas, H.
AU - Johnson, D. W.
AU - Pentheny, S.
AU - Latchaw, Richard E
PY - 1989
Y1 - 1989
N2 - Cerebral blood flow was analyzed by the stable xenon (Xe)/CT scanning technique in 29 patients with significant vascular lesions before and after administration of an acetazolamide (Diamox) vasodilatory challenge. Three response types were identified: I, normal flow before Diamox with flow augmentation after Diamox; II, low flow before Diamox with flow augmentation after Diamox; and III, low or normal flow before Diamox with no augmentation or decreased flow after Diamox. Twenty-four percent of the patients studied qualified for category III. We believe that patients in this category represent a group of individuals without blood flow reserve whose clinical management should include careful consideration of their hemodynamic status. The Xe/CT scanning technique with the addition of Diamox flow challenge is a clinically accessible and effective method for assessing cerebral blood flow and blood flow reserve.
AB - Cerebral blood flow was analyzed by the stable xenon (Xe)/CT scanning technique in 29 patients with significant vascular lesions before and after administration of an acetazolamide (Diamox) vasodilatory challenge. Three response types were identified: I, normal flow before Diamox with flow augmentation after Diamox; II, low flow before Diamox with flow augmentation after Diamox; and III, low or normal flow before Diamox with no augmentation or decreased flow after Diamox. Twenty-four percent of the patients studied qualified for category III. We believe that patients in this category represent a group of individuals without blood flow reserve whose clinical management should include careful consideration of their hemodynamic status. The Xe/CT scanning technique with the addition of Diamox flow challenge is a clinically accessible and effective method for assessing cerebral blood flow and blood flow reserve.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024359572&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024359572
VL - 10
SP - 803
EP - 810
JO - American Journal of Neuroradiology
JF - American Journal of Neuroradiology
SN - 0195-6108
IS - 4
ER -