Initial reports on the usefulness of radioimmunoassays for the beta chain of human chorionic gonadotropin and for alpha-fetopretein suggested that these 2 tests would detect metastatic non-seminomatous testicular cancer in 93 per cent of the cases. In a review of 30 patients with stages 2 and 3 non-seminomatous testicular cancer in our institutions we found a 20 per cent falsely negative rate for these serum assays. In all these cases the beta-human chorionic gonadotropin and alpha-fetoprotein levels were simultaneously negative despite proved existence of metastatic disease.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Urology|
|State||Published - 1981|
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