Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women

Wei Zheng, Timothy J. Doyle, Lawrence H. Kushi, Thomas A. Sellers, Ching Ping Hong, Aaron R. Folsom

Research output: Contribution to journalArticle

175 Citations (Scopus)

Abstract

Tea has consistently been shown to inhibit the occurrence of tumors in experimental animals. The evidence for such a beneficial effect in humans, however, is limited. The authors examined the association between non-herbal tea consumption and cancer incidence in a prospective cohort study of 35,369 postmenopausal iowa women. In this cohort, information on the frequency of tea drinking and other dietary and lifestyle factors was collected by mailed survey in 1986. After 8 years of follow-up, 2,936 incident non-skin cancer cases were ascertained in this cohort through the State Health Registry of Iowa. Proportional hazards regressions were used to derive adjusted relative risks and 95% confidence intervals for the association between tea consumption and cancer incidence. After controlling for confounding factors, the authors found that regular tea consumption was related to a slight, but not statistically significant, reduced incidence of all cancers combined. Inverse associations with increasing frequency of tea drinking were seen for cancers of the digestive tract (p for trend, 0.04) and the urinary tract (p for trend, 0.02). For women who reported drinking ≤2 cups (474 ml) of tea per day, compared with those who never or occasionally drank tea, the relative risk for digestive tract cancers was 0.68 (95% confidence interval (CI) 0.47-0.98) and for urinary tract cancers, 0.40 (95% CI 0.16-0.98). Similar inverse associations were seen for specific digestive and urinary tract cancers, although site-specific analyses were not statistically significant. No appreciable association of tea drinking was found with melanoma, non-Hodgkin's lymphoma, or cancers of the pancreas, lung, breast, uterine corpus, or ovary. This study suggests that tea, one of the most popular beverages consumed worldwide, may protect against some cancers in postmenopausal women.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalAmerican Journal of Epidemiology
Volume144
Issue number2
StatePublished - Jul 15 1996
Externally publishedYes

Fingerprint

Tea
Cohort Studies
Prospective Studies
Incidence
Neoplasms
Drinking
Urologic Neoplasms
Gastrointestinal Tract
Confidence Intervals
Beverages
Urinary Tract
Pancreatic Neoplasms
Non-Hodgkin's Lymphoma
Registries
Life Style
Ovary
Melanoma
Lung Neoplasms
Breast
Health

Keywords

  • bladder neoplasms
  • colonic neoplasms
  • diet
  • health promotion
  • neoplasms
  • prospective studies
  • tea

ASJC Scopus subject areas

  • Epidemiology

Cite this

Zheng, W., Doyle, T. J., Kushi, L. H., Sellers, T. A., Hong, C. P., & Folsom, A. R. (1996). Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women. American Journal of Epidemiology, 144(2), 175-182.

Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women. / Zheng, Wei; Doyle, Timothy J.; Kushi, Lawrence H.; Sellers, Thomas A.; Hong, Ching Ping; Folsom, Aaron R.

In: American Journal of Epidemiology, Vol. 144, No. 2, 15.07.1996, p. 175-182.

Research output: Contribution to journalArticle

Zheng, W, Doyle, TJ, Kushi, LH, Sellers, TA, Hong, CP & Folsom, AR 1996, 'Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women', American Journal of Epidemiology, vol. 144, no. 2, pp. 175-182.
Zheng W, Doyle TJ, Kushi LH, Sellers TA, Hong CP, Folsom AR. Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women. American Journal of Epidemiology. 1996 Jul 15;144(2):175-182.
Zheng, Wei ; Doyle, Timothy J. ; Kushi, Lawrence H. ; Sellers, Thomas A. ; Hong, Ching Ping ; Folsom, Aaron R. / Tea consumption and cancer incidence in a prospective cohort study of postmenopausal women. In: American Journal of Epidemiology. 1996 ; Vol. 144, No. 2. pp. 175-182.
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