Taxus sp. Intoxication in Three Francois' Langurs (Trachypithecus Francoisi)

Claude Lacasse, Kathryn C. Gamble, Robert H Poppenga, Lisa L. Farina, Jennifer Landolfi, Karen Terio

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Three Francois' langurs (Trachypithecus francoisi) were found dead, without previous clinical signs, over a 48-hour period at a zoological institution after transfer to a new exhibit. A hybrid yew shrub (Taxus baccata × T. cuspidata) was found in close proximity to the exhibit perimeter fence. Despite clinical suspicion of yew intoxication, thin-layer chromatography performed on gastric contents was negative. However, microscopic examination of gastric contents revealed multiple yew fragments, and taxine alkaloids were detected by gas chromatography and mass spectrometry of the gastric contents to confirm yew intoxication. Acute death of the animals prevented treatment. The fourth langur in the collection survived, most likely because of its low rank in the troop's hierarchy, with a suspected small amount or none of the plant ingested. To the authors' knowledge, this case report is the first yew intoxication documented in a nonhuman primate species. Taxus spp. intoxication is an often fatal condition reported in domestic animals and humans. In comparison with these species, mortality appeared delayed in the Francois' langurs, most likely because of their unique gastrointestinal anatomy, with both foregut and colonic fermentation. Plant intoxication should be a differential diagnosis when multiple acute deaths are observed after recent introduction to a new enclosure.

Original languageEnglish (US)
Pages (from-to)221-224
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Volume19
Issue number2
DOIs
StatePublished - 2007

Fingerprint

Cercopithecidae
Taxus
Gastrointestinal Contents
poisoning
stomach
Domestic Animals
Thin Layer Chromatography
Alkaloids
Gas Chromatography-Mass Spectrometry
Primates
Fermentation
Taxus cuspidata
Anatomy
death
Taxus baccata
Differential Diagnosis
foregut
fences
thin layer chromatography
domestic animals

ASJC Scopus subject areas

  • veterinary(all)
  • Microbiology

Cite this

Taxus sp. Intoxication in Three Francois' Langurs (Trachypithecus Francoisi). / Lacasse, Claude; Gamble, Kathryn C.; Poppenga, Robert H; Farina, Lisa L.; Landolfi, Jennifer; Terio, Karen.

In: Journal of Veterinary Diagnostic Investigation, Vol. 19, No. 2, 2007, p. 221-224.

Research output: Contribution to journalArticle

Lacasse, Claude ; Gamble, Kathryn C. ; Poppenga, Robert H ; Farina, Lisa L. ; Landolfi, Jennifer ; Terio, Karen. / Taxus sp. Intoxication in Three Francois' Langurs (Trachypithecus Francoisi). In: Journal of Veterinary Diagnostic Investigation. 2007 ; Vol. 19, No. 2. pp. 221-224.
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